Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331695 | 0.91 | ACE (0.56) | PPARAPPARGPTPN1ACECDC25B | |
| SCHEMBL304588 | 0.91 | ACE (0.56) | PPARAPPARGPTPN1ACECDC25B | |
| SCHEMBL3789613 | 0.90 | HDAC1 (0.49) | PPARAPPARGKDM1AHDAC1ITGB3 | |
| SCHEMBL26347313 | 0.84 | ACE (0.49) | PPARAPPARGKDM1AITGB3ITGA2B | |
| SCHEMBL29034539 | 0.84 | ACE (0.49) | PPARAPPARGKDM1AITGB3ITGA2B | |
| SCHEMBL305197 | 0.82 | CYP19A1 (0.49) | HDAC1CYP19A1 | |
| SCHEMBL335310 | 0.81 | ITGB3 (0.67) | PPARAPPARGITGB3ITGA2BITGA4 | |
| SCHEMBL335309 | 0.81 | ITGB3 (0.67) | PPARAPPARGITGB3ITGA2BITGA4 | |
| SCHEMBL1308867 | 0.81 | ITGB3 (0.67) | PPARAPPARGITGB3ITGA2BITGA4 | |
| SCHEMBL756405 | 0.81 | PTPN1 (0.49) | PPARAPPARGPTPN1ACECDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210882-A1 | Synthesis of new protected azahistidine, their processes and their use in synthesises | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2010-07-28 | — | — | EP | disclosed |
| WO-2010081882-A2 | SYNTHESIS OF NEW PROTECTED AZAHISTIDINES, THEIR PROCESSES AND THEIR USE IN SYNTHESISES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2010-07-22 | — | — | WO | disclosed |