Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368354 | 0.95 | CYP2A6 (0.56) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL9347766 | 0.93 | CYP2A6 (0.55) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL9347729 | 0.93 | CYP2A6 (0.55) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL91191 | 0.89 | CYP2A6 (0.62) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL6690187 | 0.82 | DRD2 (0.52) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP | |
| SCHEMBL5546079 | 0.81 | CYP2A6 (0.58) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL79170 | 0.81 | CYP2A6 (0.69) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL81236 | 0.81 | CYP2A6 (0.58) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL5235492 | 0.81 | CYP2A6 (0.67) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL10670791 | 0.81 | IDO1 (0.54) | CYP2A6IDO1ALDH1A1CHRNA7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11193157-B2 | Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system | CODEXIS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200181672-A1 | PROCESSES USING AMINO ACID DEHYDROGENASES AND KETOREDUCTASE-BASED COFACTOR REGENERATING SYSTEM | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2020-06-11 | — | — | US | disclosed |
| US-10016401-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-9871211-B2 | Electroactive materials | EI DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-16 | — | — | US | disclosed |
| US-20170338423-A9 | ELECTROACTIVE MATERIALS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170326116-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2017-11-16 | — | — | US | disclosed |
| US-7645400-B2 | Composition containing carbon nanotubes having a coating | MITSUBISHI RAYON CO., LTD. (JP) | 2010-01-12 | — | — | US | disclosed |
| US-20090321688-A1 | Carbon Nanotube Composition, Composite Having a Coated Film Composed of the Same, and Their Production Methods | MITSUBISHI RAYON CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20060052509-A1 | Composition containing carbon nanotubes having coating thereof and process for producing them | MITSUBISHI RAYON CO., LTD. (JP) | 2006-03-09 | — | — | US | disclosed |
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10016401-B2 | Histone demethylase inhibitors | KDM1B, KDM1A, KDM5A | CYP2A6 2111/4885IDO1 371/4885ALDH1A1 437/4885 |
| US-20170338423-A9 | ELECTROACTIVE MATERIALS | KCNN4, RCOR3, HCN4 | CYP2A6 3076/4885IDO1 2180/4885ALDH1A1 3134/4885 |
| US-20170326116-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM5A | CYP2A6 2111/4885IDO1 371/4885ALDH1A1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.