Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580112 | 0.90 | PTPRA (0.82) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL1580111 | 0.90 | PTPRA (0.82) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL5115733 | 0.81 | PTPRA (0.67) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL5115727 | 0.81 | PTPRA (0.67) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL30381729 | 0.81 | PTPRA (1.00) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL2965137 | 0.81 | PTPRA (1.00) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL145392 | 0.81 | PTPRA (1.00) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL3519524 | 0.81 | PTPRA (1.00) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL30789181 | 0.81 | PTPRA (1.00) | PTPRACYP2C19KMT2AKDM4ELMNA | |
| SCHEMBL14032218 | 0.79 | PTPRA (0.60) | PTPRACYP2C19KDM4EMAPTNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398495-A1 | MODIFIED NON-CYTOTOXIC PROTEASES | Syntaxin Limited (GB) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010094905-A1 | MODIFIED NON-CYTOTOXIC PROTEASES | SYNTAXIN LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |
| EP-1007070-A4 | PROLONGING SURVIVAL OF TRANSPLANTED PANCREATIC CELLS | BIOMEASURE INC (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1007070-A1 | PROLONGING SURVIVAL OF TRANSPLANTED PANCREATIC CELLS | Biomeasure Incorporated (US) | 2000-06-14 | — | — | EP | disclosed |
| EP-0980253-A1 | SOMATOSTATIN AND SOMATOSTATIN AGONISTS FOR TREATING INSULIN INSENSITIVITY AND SYNDROME X | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998051332-A1 | SOMATOSTATIN AND SOMATOSTATIN AGONISTS FOR TREATING INSULIN INSENSITIVITY AND SYNDROME X | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (S.C.R.A.S.) (FR) | 1998-11-19 | — | — | WO | disclosed |
| WO-1998008528-A1 | METHOD OF INHIBITING FIBROSIS WITH A SOMATOSTATIN AGONIST | BIOMEASURE INCORPORATED (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1997037675-A1 | PROLONGING SURVIVAL OF TRANSPLANTED PANCREATIC CELLS | BIOMEASURE INCORPORATED (US) | 1997-10-16 | — | — | WO | disclosed |