SCHEMBL3519524

SCHEMBL3519524

NC(Cc1c[nH]c2cc([N+](=O)[O-])ccc12)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRA P18433 1/20 1.00
CYP2C19 P33261 1/20 0.95
KMT2A Q03164 3/20 0.60
KDM4E B2RXH2 2/20 0.60
LMNA P02545 2/20 0.60
MAPT P10636 2/20 0.60
TSHR P16473 2/20 0.60
BLM P54132 2/20 0.60
PMP22 Q01453 2/20 0.60
MEN1 O00255 2/20 0.60
MPO P05164 1/20 0.60
HIF1A Q16665 1/20 0.60
ALDH1A1 P00352 1/20 0.56
CYP3A4 P08684 1/20 0.56
HTR1A P08908 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
ALOX15 P16050 1/20 0.56
NFKB1 P19838 1/20 0.56
HTR2A P28223 1/20 0.56
HTR2C P28335 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2965137 1.00 PTPRA (1.00) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL30789181 1.00 PTPRA (1.00) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL30381729 1.00 PTPRA (1.00) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL145392 1.00 PTPRA (1.00) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL1580111 0.90 PTPRA (0.82) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL1580112 0.90 PTPRA (0.82) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL22288108 0.86 PTPRA (0.75) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL20931031 0.86 PTPRA (0.75) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL22288107 0.86 PTPRA (0.75) PTPRACYP2C19KMT2AKDM4ELMNA
SCHEMBL7380735 0.85 PTPRA (0.73) PTPRACYP2C19KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4034248-B1 COMPOSITE BIOMARKER FOR CANCER THERAPY BRISTOL MYERS SQUIBB CO (US) 2026-05-20 EP claimed
US-11752131-B2 Methods and pharmaceutical compositions for the treatment of obesity INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2023-09-12 US claimed
WO-2008068621-A2 COMBINATION PRODUCT WITH IDO INHIBITOR AND TUMOR TARGETED IFN-GAMMA MOLMED SPA (IT) 2008-06-12 WO claimed
EP-3906415-B1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER INST NAT SANTE RECH MED (FR) 2026-04-15 EP disclosed
US-20260083725-A1 SIGMARI LIGAND FOR THE TREATMENT OF PANCREATIC CANCER INST NAT SANTE RECH MED (FR) 2026-03-26 US disclosed
EP-4713371-A1 ANTI-CATHEPSIN-D ANTIBODIES Institut National de la Santé et de la Recherche Médicale (FR) 2026-03-25 EP disclosed
US-20260061031-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DILATED CARDIOMYOPATHY INST NAT SANTE RECH MED (FR) 2026-03-05 US disclosed
EP-4689658-A1 METHOD FOR DISCRIMINATING MONO-IMMUNOTHERAPY FROM COMBINED IMMUNOTHERAPY IN CANCERS Institut National de la Santé et de la Recherche Médicale (FR) 2026-02-11 EP disclosed
US-20260035471-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER INST NAT SANTE RECH MED (FR) 2026-02-05 US disclosed
US-20260029406-A1 PROTEIN IDENTIFICATION VIA PEPTIDE BARCODES Quantum-Si Incorporated (US) 2026-01-29 US disclosed
US-20260023081-A1 SOLID PHASE LIBRARY PREPARATION FOR POLYPEPTIDE SEQUENCING Quantum-Si Incorporated (US) 2026-01-22 US disclosed
US-20090081155-A1 Use of Inhibitors of Indoleamine-2,3-Dioxygenase in Combination with Other Therapeutic Modalities MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC (US) 2009-03-26 US disclosed
EP-1981534-A2 INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS Medical College of Georgia Research Institute, Inc (US) 2008-10-22 EP disclosed
CN-101265259-A Novel IDO inhibitor and its usage method LANKENAU INST MEDICAL RES (US) 2008-09-17 CN disclosed
CN-101265254-A Novel IDO inhibitor and its usage method LANKENAU INST MEDICAL RES (US) 2008-09-17 CN disclosed
EP-1937303-A2 THE INDUCTION OF INDOLEAMINE 2,3-DIOXYGENASE IN DENDRITIC CELLS BY TLR LIGANDS AND USES THEREOF Medical College Of Georgia Research Institute, Inc. (US) 2008-07-02 EP disclosed
WO-2008068621-A2 COMBINATION PRODUCT WITH IDO INHIBITOR AND TUMOR TARGETED IFN-GAMMA MOLMED SPA (IT) 2008-06-12 WO disclosed
WO-2007081878-A2 INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) 2007-07-19 WO disclosed
WO-2007050405-A2 THE INDUCTION OF INDOLEAMINE 2,3-DIOXYGENASE IN DENDRITIC CELLS BY TLR LIGANDS AND USES THEREOF MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) 2007-05-03 WO disclosed
US-20040234623-A1 Anticancer agents; infection; immunosuppressants MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) 2004-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061031-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DILATED CARDIOMYOPATHY CD274, PDCD1, ICOS PTPRA 1833/4885CYP2C19 3111/4885KMT2A 3766/4885
US-11752131-B2 Methods and pharmaceutical compositions for the treatment of obesity IDO1, IDO2, GPR119 PTPRA 2977/4885CYP2C19 313/4885KMT2A 1002/4885
US-20260083725-A1 SIGMARI LIGAND FOR THE TREATMENT OF PANCREATIC CANCER SCTR, NGFR, SIGMAR1 PTPRA 355/4885CYP2C19 4875/4885KMT2A 4372/4885
US-20260029406-A1 PROTEIN IDENTIFICATION VIA PEPTIDE BARCODES MAX, DNMT3A, SET PTPRA 1651/4885CYP2C19 4218/4885KMT2A 100/4885
US-20260023081-A1 SOLID PHASE LIBRARY PREPARATION FOR POLYPEPTIDE SEQUENCING SPPL2B, SPPL2A, CTRC PTPRA 4759/4885CYP2C19 1876/4885KMT2A 1552/4885
US-20260035471-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER CD274, PDCD1LG2, PDCD1 PTPRA 541/4885CYP2C19 4543/4885KMT2A 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.