Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760612 | 0.95 | POLB (0.64) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL3749019 | 0.93 | GAA (0.49) | POLBALDH1A1TSHRGAAMEN1 | |
| SCHEMBL29838840 | 0.82 | POLB (0.75) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL1058665 | 0.82 | POLB (0.75) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL14433714 | 0.82 | POLB (0.75) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL13589979 | 0.82 | POLB (0.75) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL14493662 | 0.82 | POLB (0.75) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL11577622 | 0.82 | GAA (0.60) | POLBALDH1A1TSHRGAAMEN1 | |
| SCHEMBL6865696 | 0.77 | POLB (0.68) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL1788313 | 0.75 | POLB (0.66) | POLBALDH1A1TSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138828-A2 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | disclosed |