Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789988 | 0.93 | POLB (0.58) | GAAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL11577622 | 0.88 | GAA (0.60) | GAAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL3760612 | 0.87 | POLB (0.64) | GAAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL10532442 | 0.79 | GAA (0.51) | GAAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL25909650 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KMT2ATSHR | |
| SCHEMBL1074062 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KMT2ATSHR | |
| SCHEMBL15536893 | 0.78 | ALDH1A1 (0.45) | GAAPOLBALDH1A1THRB | |
| SCHEMBL25245007 | 0.77 | — | — | |
| SCHEMBL21376621 | 0.74 | ALDH1A1 (0.66) | GAAALDH1A1KMT2ATHRBTSHR | |
| SCHEMBL7571363 | 0.74 | GRIN2D (0.56) | GAAPOLBMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962639-B2 | Potassium channel modulators | ABBVIE INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20100305109-A1 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305109-A1 | POTASSIUM CHANNEL MODULATORS | KCNQ1, KCNQ2, KCNJ2 | GAA 2874/4885POLB 4177/4885ALDH1A1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.