SCHEMBL379076

SCHEMBL379076

O=C(O)CCc1cccc(-c2cccc(OCc3ccccc3)c2)c1

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 16/20 0.73
FFAR4 Q5NUL3 6/20 0.73
AKR1B1 P15121 1/20 0.73
NR4A2 P43354 1/20 0.60
MRGPRX4 Q96LA9 1/20 0.60
PTGER4 P35408 1/20 0.60
PTGER3 P43115 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17413684 0.93 FFAR1 (0.80) FFAR1FFAR4AKR1B1NR4A2MRGPRX4
SCHEMBL8339114 0.92 FFAR1 (0.78) FFAR1FFAR4AKR1B1MRGPRX4PTGER4
SCHEMBL2772855 0.91 FFAR1 (0.83) FFAR1FFAR4AKR1B1NR4A2
SCHEMBL18165304 0.90 FFAR1 (0.85) FFAR1FFAR4AKR1B1PTGER4PTGER3
SCHEMBL18165300 0.89 FFAR1 (0.67) FFAR1FFAR4AKR1B1NR4A2MRGPRX4
SCHEMBL22540400 0.86 FFAR1 (0.62) FFAR1FFAR4AKR1B1NR4A2MRGPRX4
SCHEMBL3908596 0.85 CFD (0.66) FFAR1FFAR4AKR1B1NR4A2MRGPRX4
SCHEMBL1747107 0.84 FFAR1 (1.00) FFAR1FFAR4AKR1B1
SCHEMBL18165298 0.83 FFAR1 (0.64) FFAR1FFAR4AKR1B1
SCHEMBL7347912 0.83 FFAR1 (0.69) FFAR1FFAR4AKR1B1PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8313669-B2 Liquid-crystal display MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 2012-11-20 US disclosed
US-8313669-B2 Liquid-crystal display MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 2012-11-20 US disclosed
US-8313669-B2 Liquid-crystal display MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 2012-11-20 US disclosed
EP-2181174-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2012-01-25 EP disclosed
EP-2181174-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2012-01-25 EP disclosed
US-20110101269-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-05 US disclosed
US-20110101269-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-05 US disclosed
US-20110101269-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-05 US disclosed
EP-2181174-A1 LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2010-05-05 EP disclosed
WO-2009030322-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed
WO-2009030322-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110101269-A1 LIQUID-CRYSTAL DISPLAY KLK3, LPXN, PSAP FFAR1 2706/4885FFAR4 2160/4885AKR1B1 4167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.