Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Seocalcitol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR known ✓ | P11473 | 13/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.70 |
| ▸ | PGR | P06401 | 2/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | GC | P02774 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Seocalcitol SCHEMBL12028975 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL5003622 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL29836063 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL14146667 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL1229451 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL5003623 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL24066895 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL8219733 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL3790 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR | |
| Seocalcitol SCHEMBL14112510 | 1.00 | VDR (1.00) | VDRADORA3SLC6A2NR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4102 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250339399-A1 | SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM | BEIJING CREATRON INSTITUTE OF PHARMACEUTICAL RES CO LTD (CN) | 2025-11-06 | — | — | US | claimed |
| US-12364682-B2 | Use of tegaserod in preparation of anti-tumor drug | QINGDAO HAIJI BIOMEDICINE CO., LTD. (CN) | 2025-07-22 | — | — | US | claimed |
| WO-2025129271-A1 | LIPID DELIVERY VEHICLE | THE UNIVERSITY OF QUEENSLAND (AU) | 2025-06-26 | — | — | WO | claimed |
| WO-2025111447-A1 | TREATMENT OF CANCER WITH DRUG COMBINATIONS | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (US) | 2025-05-30 | — | — | WO | claimed |
| WO-2025108575-A1 | METHODS OF SELECTIVE DEPROTECTION AND SYNTHESIS OF TRANSHYDRINDANE- SKELETON-BASED COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 2025-05-30 | — | — | WO | claimed |
| US-20250059301-A1 | Fusion Protein Construct | NORTHWESTERN UNIVERSITY | 2025-02-20 | — | — | US | claimed |
| US-20230398130-A1 | METHODS AND COMPOSITIONS FOR DIFFERENTIATING STEM CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-12-14 | — | — | US | claimed |
| CN-117126090-A | Impurity removal method for 5,6-trans impurities in calcitol bulk drug | 正大制药（青岛）有限公司 | 2023-11-28 | — | — | CN | claimed |
| WO-2023225206-A1 | METHOD FOR ENHANCING REMYELINATION VIA CO-ADMINISTRATION OF MUSCARINIC RECEPTOR ANTAGONISTS AND VITAMIN D ANALOGUES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-23 | — | — | WO | claimed |
| EP-4232012-A1 | METHODS AND COMPOSITIONS FOR DIFFERENTIATING STEM CELLS | Massachusetts Institute of Technology (US) | 2023-08-30 | — | — | EP | claimed |
| US-20020183277-A1 | Combination of vitamin D analogue and pyrimidine nucleoside analogue | BINDERUP LISE (DK) | 2002-12-05 | — | — | US | claimed |
| WO-2002094813-A1 | NOVEL PYRIDYL CYANOGUANIDINE COMPOUNDS | LEO PHARMA A/S (DK) | 2002-11-28 | — | — | WO | claimed |
| CN-1382036-A | Solubilized pharmaceutical composition for parenteral administration | LEO PHARM PROD LTD (DK) | 2002-11-27 | — | — | CN | claimed |
| WO-2002092062-A2 | COMBINATION OF VITAMIN D ANALOGUE AND PYRIMIDINE NUCLEOSIDE ANALOGUE | LEO PHARMA A/S (DK) | 2002-11-21 | — | — | WO | claimed |
| US-20020111336-A1 | Topical composition | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2002-08-15 | — | — | US | claimed |
| WO-2002034235-A1 | TOPICAL COMPOSITION CONTAINING AT LEAST ONE VITAMIN D OR ONE VITAMIN D ANALOGUE AND AT LEAST ONE CORTICOSTEROID | LEO PHARMA A/S (DK) | 2002-05-02 | — | — | WO | claimed |
| EP-1178808-A1 | PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2002-02-13 | — | — | EP | claimed |
| EP-1171100-A1 | SOLUBILIZED PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2002-01-16 | — | — | EP | claimed |
| WO-2000064450-A1 | PHARMACEUTICAL COMPOSITION | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 2000-11-02 | — | — | WO | claimed |
| WO-2000061112-A2 | SOLUBILIZED PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 2000-10-19 | — | — | WO | claimed |