Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23786184 | 0.99 | MAPT (0.47) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL3791891 | 0.89 | MAPT (0.45) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL28845231 | 0.86 | KMT2A (0.55) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL23705193 | 0.86 | KMT2A (0.55) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL21113593 | 0.86 | KMT2A (0.55) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL23786318 | 0.85 | MAPT (0.47) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL23786301 | 0.81 | ALDH1A1 (0.48) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL20402644 | 0.81 | MAPT (0.57) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL23705089 | 0.81 | MAPT (0.57) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL21531212 | 0.80 | MAPT (0.52) | MAPTKDM4EALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741014-B2 | Patterning and alteration of molecules | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-06-22 | — | — | US | disclosed |
| US-20070000866-A1 | Patterning and alteration of molecules | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-01-04 | — | — | US | disclosed |
| US-20060138083-A1 | Patterning and alteration of molecules | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-06-29 | — | — | US | disclosed |