SCHEMBL379255

SCHEMBL379255

CC(O)CNC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3853943 1.00
SCHEMBL6319825 1.00
SCHEMBL24238507 0.80 ADH1B (0.52)
SCHEMBL13283251 0.77 ADH1B (0.68)
SCHEMBL26236 0.77
SCHEMBL3670984 0.77
SCHEMBL23766640 0.77 ADH1B (0.52)
SCHEMBL17275391 0.75
SCHEMBL19390046 0.74
SCHEMBL2957915 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104350076-A Polymer and nanogel materials, and methods of making and using the same JOHNSON & JOHNSON VISION CARE 2015-02-11 CN claimed
EP-2331503-B1 4-PHENOXYMETHYLPIPERIDINES AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2013-08-21 EP claimed
US-8334288-B2 4-phenoxymethylpiperidines as modulators of GPR119 activity IRM LLC (BM) 2012-12-18 US claimed
JP-2011527701-A 2011-11-04 JP claimed
US-20110190298-A1 4-PHENOXYMETHYLPIPERIDINES AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2011-08-04 US claimed
EP-2331503-A1 4-PHENOXYMETHYLPIPERIDINES AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2011-06-15 EP claimed
WO-2010006191-A1 4-PHENOXYMETHYLPIPERIDINES AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2010-01-14 WO claimed
EP-1306085-B1 2-Cyclohexyl-4-phenyl-1H-imidazole derivatives as ligands for the neuropeptide Y5 receptor NEUROGEN CORP (US) 2007-02-14 EP claimed
US-4315855-A Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
WO-2024114814-A1 JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS ONQUALITY PHARMACEUTICALS CHINA LTD (CN) 2024-06-06 WO disclosed
CN-117916368-A Base editing of thyroxine transporter genes 比姆医疗股份有限公司 2024-04-19 CN disclosed
US-20190134052-A1 DOSAGE REGIMEN FOR A PI-3 KINASE INHIBITOR NOVARTIS AG (CH) 2019-05-09 US disclosed
US-20170182176-A1 POLYMERS HAVING THERAPEUTICALLY ACTIVE AGENTS CONJUGATED THERETO, PROCESSES OF PREPARING SAME AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2017-06-29 US disclosed
US-9687562-B2 Polymers having therapeutically active agents conjugated thereto, processes of preparing same and uses thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2017-06-27 US disclosed
EP-0701998-A1 Catalyst for production of tertiary n-alkenyl carboxylic acid amide, and process for production of tertiary n-alkenyl carboxylic acid amide using said catalyst NIPPON SHOKUBAI CO., LTD. (JP) 1996-03-20 EP disclosed
WO-1995019959-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PHOSPHOLIPASE A2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-07-27 WO disclosed
US-5362736-A Alkoxy derivatives for cardiovascular disorders BANYU PHARMACEUTICAL CO., LTD. (JP) 1994-11-08 US disclosed
EP-0501693-A1 Isoquinoline derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-09-02 EP disclosed
US-4315855-A Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US disclosed
US-3979378-A Water-soluble azo dyes having a substituted 2-hydroxypyridone (6) coupling component BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-09-07 US disclosed