SCHEMBL379300

SCHEMBL379300

CCN(CC)CCC[SiH2]C(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379354 0.94 SIGMAR1 (0.35) SIGMAR1ALDH1A1
SCHEMBL15611858 0.87 BCHE (0.33) ALDH1A1
SCHEMBL329588 0.87
SCHEMBL379786 0.87
SCHEMBL15611960 0.83 MEN1 (0.38)
SCHEMBL15611706 0.83 BCHE (0.33) ALDH1A1
SCHEMBL7898957 0.82 PAOX (0.35)
SCHEMBL379493 0.82 SIGMAR1 (0.32) SIGMAR1
SCHEMBL5072127 0.80 LCK (0.34)
SCHEMBL15675773 0.80 LCK (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141426-A1 ALKANOLAMINE-CONTAINING MEMBRANES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2023-07-27 WO claimed
CN-121574305-A Preparation method of styrene-butadiene rubber for semisteel tread 万华化学集团股份有限公司 2026-02-27 CN disclosed
EP-4662253-A2 METHOD FOR PREPARING MONOMODAL POLYISOPRENE WITH DILITHIUM INITIATORS BRIDGESTONE CORPORATION (JP) 2025-12-17 EP disclosed
EP-4646450-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2025-11-12 EP disclosed
US-20250179221-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-06-05 US disclosed
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed
US-20250109282-A1 NATURAL RUBBER COMPOSITIONS FOR PNEUMATIC TIRES BRIDGESTONE CORPORATION (JP) 2025-04-03 US disclosed
CN-118900883-A Highly functionalized stable hydrocarbyloxysilyl polydienes and polydiene copolymers 普利司通美国轮胎运营有限责任公司 2024-11-05 CN disclosed
CN-118660937-A Natural rubber composition for pneumatic tire 株式会社普利司通 2024-09-17 CN disclosed
EP-2366557-A1 Tire rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
EP-2366558-A1 Tire rubber composition and heavy-load tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
US-20110146877-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
EP-2266819-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME Bridgestone Corporation (JP) 2010-12-29 EP disclosed
EP-2196324-A1 Tread rubber composition for studless tire and studless tire Sumitomo Rubber Industries, Ltd. (JP) 2010-06-16 EP disclosed
US-20100144954-A1 TREAD RUBBER COMPOSITION FOR STUDLESS TIRE AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-06-10 US disclosed
EP-2184317-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
US-20100108213-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2174801-A2 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2010-04-14 EP disclosed
US-20100084065-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME HRH3, HRH4, OR10J3 SIGMAR1 176/4885ALDH1A1 3683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.