SCHEMBL379309

SCHEMBL379309

CCn1cc(C=O)c2ccccc21

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
MAPT P10636 3/20 0.61
IMPDH2 P12268 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.59
HTT P42858 3/20 0.59
POLB P06746 3/20 0.58
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
LMNA P02545 2/20 0.56
HPGD P15428 1/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
USP2 O75604 1/20 0.55
ATM Q13315 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30512327 1.00 ALDH1A1 (0.62) ALDH1A1MEN1KMT2AMAPTIMPDH2
SCHEMBL21591573 0.88 MEN1 (0.57) ALDH1A1MEN1KMT2AMAPTIMPDH2
SCHEMBL31516344 0.86 POLB (0.62) ALDH1A1MEN1KMT2AMAPTIMPDH2
SCHEMBL14448832 0.86 POLB (0.62) ALDH1A1MEN1KMT2AMAPTIMPDH2
Morpholine SCHEMBL29277404 0.85 MEN1 (0.52) ALDH1A1MEN1KMT2AMAPTIMPDH2
SCHEMBL10654842 0.84 MEN1 (0.59) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL16116060 0.83 ALDH1A1 (0.66) ALDH1A1MAPTIMPDH2SMN1; SMN2HTT
SCHEMBL28814399 0.83 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AMAPTIMPDH2
SCHEMBL11903655 0.82 ALDH1A1 (0.64) ALDH1A1MAPTIMPDH2SMN1; SMN2HTT
SCHEMBL24668878 0.82 MEN1 (0.61) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263933-A Alpha-carboline derivative and synthesis method thereof 湘潭大学 2023-12-22 CN claimed
CN-116574048-A Bromination reaction method of remote indole C-H bond by using sunlight catalysis 陕西科技大学 2023-08-11 CN claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
CN-116535386-B Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof 西南大学 2025-05-27 CN disclosed
CN-117263933-A Alpha-carboline derivative and synthesis method thereof 湘潭大学 2023-12-22 CN disclosed
CN-116574048-A Bromination reaction method of remote indole C-H bond by using sunlight catalysis 陕西科技大学 2023-08-11 CN disclosed
CN-116535386-A Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof 西南大学 2023-08-04 CN disclosed
CN-112661750-B Ketene-bridged quinazolinone thiazole compound and preparation method and application thereof 西南大学 2022-10-21 CN disclosed
CN-112921346-B Electrochemical synthesis method of 3-formyl indole derivative 浙江工业大学 2022-07-08 CN disclosed
CN-112921346-A Electrochemical synthesis method of 3-formyl indole derivative 浙江工业大学 2021-06-08 CN disclosed
US-4340624-A STYRYL-LIKE COMPOUNDS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-07-20 US disclosed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US disclosed
US-4139274-A Apparatus for changing color MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-02-13 US disclosed
US-4072519-A Photoconductive composition, and element XEROX CORPORATION (US) 1978-02-07 US disclosed
US-4003633-A Color display device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-01-18 US disclosed
US-4002616-A POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-11 US disclosed
US-3962220-A ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed
US-3962221-A CONDENSATION, REDUCTION, OXIDATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed