SCHEMBL3793391

SCHEMBL3793391

C=CC(=O)OC(=O)C(C)=CC.[NaH]

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
TSHR P16473 7/20 0.34
HPGD P15428 1/20 0.33
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140460 1.00 ALDH1A1 (0.38) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL775246 0.98 ALDH1A1 (0.39) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL28769595 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL7557966 0.81 ALDH1A1 (0.41) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL28204922 0.80 ALDH1A1 (0.36) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL22289171 0.80 ALDH1A1 (0.36) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL27864576 0.80 ALDH1A1 (0.36) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL27139228 0.80 ALDH1A1 (0.36) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL28085790 0.80 ALDH1A1 (0.36) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL28096807 0.79 ALDH1A1 (0.32) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723412-B2 Stabilization of thermoplastic nanocomposites CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
EP-1824919-B1 STABILIZED ORGANIC MATERIALS CONTAINING FILLERS BASF SE (DE) 2009-12-09 EP disclosed
US-20090298978-A1 Stabilized organic materials containing fillers CIBA SPECIALTY CHEMICALS CORP. 2009-12-03 US disclosed
EP-1592741-B1 STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES CIBA HOLDING INC (CH) 2009-01-14 EP disclosed
US-20080194743-A1 processing stabilizer selected from the group consisting of hydroxylamine stabilizers, and an antistatic agent selected from an ethoxylated amine and/or an ethoxylated amide, as stabilizers for protecting organic materials ROTZINGER BRUNO 2008-08-14 US disclosed
US-7375149-B2 Stabilization of organic materials CIBA SPECIALTY CHEMICALS CORP. (US) 2008-05-20 US disclosed
US-20060167146-A1 Stabillization of organic materials CIBA SPECIALTY CHEMICALS CORP. 2006-07-27 US disclosed
US-20060122308-A1 Stabilization of thermoplastic nanocomposites CIBA SPECIALTY CHEMICALS CORP. 2006-06-08 US disclosed
EP-1592741-A1 STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
EP-1539873-A2 STABILLIZATION OF ORGANIC MATERIALS Ciba SC Holding AG (CH) 2005-06-15 EP disclosed
WO-2004063268-A1 STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-29 WO disclosed
WO-2004024810-A2 STABILLIZATION OF ORGANIC MATERIALS CIBA, SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-03-25 WO disclosed
EP-1149133-B1 SYNTHETIC POLYMERS COMPRISING ADDITIVE BLENDS WITH ENHANCED EFFECT CIBA SC HOLDING AG (CH) 2004-03-17 EP disclosed
US-6610765-B1 Excellent stability against oxidative, thermal or light degradation; polymeric dispersing or solvating agent having amphiphilic properties; polyacrylates, polysiloxanes, polyvinyl acetate or block copolymers CIBA SPECIALTY CHEMICALS CORPORATION 2003-08-26 US disclosed
EP-1149133-A2 SYNTHETIC POLYMERS COMPRISING ADDITIVE BLENDS WITH ENHANCED EFFECT Ciba SC Holding AG (CH) 2001-10-31 EP disclosed
WO-2000042109-A2 SYNTHETIC POLYMERS COMPRISING ADDITIVE BLENDS WITH ENHANCED EFFECT CIBA SPECIALTY CHEMICALS HOLDING, INC. (CH) 2000-07-20 WO disclosed