SCHEMBL37935

SCHEMBL37935

O=C(Cl)/C=C/c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.67
LMNA P02545 3/20 0.67
HDAC3 O15379 2/20 0.67
HDAC4 P56524 2/20 0.67
HDAC1 Q13547 2/20 0.67
HDAC2 Q92769 2/20 0.67
HDAC8 Q9BY41 2/20 0.67
HDAC6 Q9UBN7 2/20 0.67
PLIN1 O60240 2/20 0.67
RECQL P46063 2/20 0.67
PLIN5 Q00G26 2/20 0.67
ABHD5 Q8WTS1 2/20 0.67
ALDH1A1 P00352 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
F3 P13726 2/20 0.67
TNKS O95271 1/20 0.67
HCAR2 Q8TDS4 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC10 Q969S8 1/20 0.67
HDAC11 Q96DB2 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6031974 1.00 MAPT (0.67) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL37936 1.00 MAPT (0.67) MAPTLMNAHDAC3HDAC4HDAC1
Fluoride SCHEMBL28142752 0.98 MAPT (0.64) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL27826046 0.98 MAPT (0.64) MAPTLMNAHDAC3HDAC4HDAC1
Water SCHEMBL28081094 0.98 MAPT (0.64) MAPTLMNAHDAC3HDAC4HDAC1
Chloroform SCHEMBL28195040 0.94 MAPT (0.59) MAPTLMNAHDAC3HDAC4HDAC1
Chloroform SCHEMBL28195041 0.94 MAPT (0.59) MAPTLMNAHDAC3HDAC4HDAC1
Acetone SCHEMBL29037563 0.94 TDP1 (0.67) MAPTLMNAHDAC3HDAC4HDAC1
Aziridine SCHEMBL3858495 0.92 MAPT (0.57) MAPTLMNAHDAC3HDAC4HDAC1
Phenol SCHEMBL2476801 0.92 MAPT (0.59) MAPTLMNAHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6271 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031284-A Sun-proof particles with multilayer core-shell structure and preparation method and application thereof 广州极钛美纳米科技有限公司 2026-05-15 CN claimed
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof ISP INVESTMENTS LLC (US) 2026-02-17 US claimed
CN-120131504-A Nicotinamide anti-inflammatory emulsion and preparation method thereof 厚福生物科技江苏有限公司 2025-06-13 CN claimed
CN-116768750-B Diphenol monomer containing photo-curable cinnamate group, preparation method of diphenol monomer, photosensitive polyaryletherketone, preparation method of photosensitive polyaryletherketone and application of photosensitive polyaryletherketone 兰州大学 2025-05-30 CN claimed
CN-120058679-A Cinnamamide 3CL protease covalent inhibitor, preparation method thereof and application thereof in preparation of anti-coronavirus drugs 陕西科技大学 2025-05-30 CN claimed
CN-119899160-A Cinnamic acid-type phyllanthin A derivative and preparation method and application thereof 湖南化工职业技术学院 2025-04-29 CN claimed
CN-119777031-A Polysaccharide-based thermoplastic composite fiber and preparation method thereof 中国科学院化学研究所 2025-04-08 CN claimed
CN-119764640-A Chemical soaking discharge method for waste sodium ion battery 浙江华宇钠电新能源科技有限公司 2025-04-04 CN claimed
WO-2025059259-A1 NEW PROCESS FOR PHENYLEPHRINE AND SALBUTAMOL AND RELATED COMPOUNDS VIA ASYMETRIC TRANSFER HYDROGENATION OF UNPROTECTED AMINO KETONES VIRGINIA COMMONWEALTH UNIVERSITY (US) 2025-03-20 WO claimed
CN-119642084-A Fireproof high-pressure hydrogen storage cylinder and preparation method thereof 沈阳欧施盾新材料科技有限公司 2025-03-18 CN claimed
EP-0299565-A2 Optical products made from a thermosetting copolymer having an index of refraction nD20 - 1,52 AKZO N.V. (NL) 1989-01-18 EP claimed
US-4735891-A PRINTED MULTILAYER CIRCUITS BY COATING METAL FOIL, EXPOSURE, AND DEVELOPMENT SIEMENS AKTIENGESELLSCHAFT (DE) 1988-04-05 US claimed
US-4599406-A ANHYDRIDING, AMIDATION, ANTIINFLAMMATORY AGENTS SPA-SOCIETA PRODOTTI ANTIBIOTICI SPA (IT) 1986-07-08 US claimed
EP-0094283-B1 SUSTAINED-RELEASE THEOPHYLLIN DRUG FORMULATION LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1985-11-21 EP claimed
EP-0079639-B1 A NEW ANTI-INFLAMMATORY DRUG SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. (IT) 1985-07-24 EP claimed
EP-0146102-A2 Process for preparing benzothiazine compounds SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. (IT) 1985-06-26 EP claimed
EP-0079639-A1 A new anti-inflammatory drug SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. (IT) 1983-05-25 EP claimed
US-4374918-A GELS, LATEX, AND TWO-COMPONENT CHARGE CONTROL AGENT; ELECTROSTATICS NASHUA CORPORATION (US) 1983-02-22 US claimed
US-4310641-A POLYAMIDE-IMIDE MODIFIED WITH A CINNAMOYL GROUP ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-01-12 US claimed
US-4025580-A ACYLATION IN PRESENCE OF LEWIS ACID CATALYST; BIODEGRADABLE PACKAGING OWENS-ILLINOIS, INC. (US) 1977-05-24 US claimed