Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269915 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL4559573 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL4559570 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL3682579 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL4559828 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL4559831 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL3794524 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL2020730 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL1151027 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL2020733 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573188-A2 | Process for the production of fine chemicals | Metanomics GmbH (DE) | 2013-03-27 | — | — | EP | claimed |
| US-20070092461-A1 | Novel Hydroxy Acid Complexes for Antiaging and Skin Renovation | BIODERM RESEARCH (US) | 2007-04-26 | — | — | US | claimed |
| WO-2006084174-A2 | IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ALKALINE PHARMACEUTICAL DRUGS | YU RUEY J (US) | 2006-08-10 | — | — | WO | claimed |
| US-20060110415-A1 | Topical Delivery System for Cosmetic and Pharmaceutical Agents | BIODERM RESEARCH (US) | 2006-05-25 | — | — | US | claimed |
| EP-1601366-A1 | IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ALKALINE PHARMACEUTICAL DRUGS | Yu, Ruey J., Dr. (US) | 2005-12-07 | — | — | EP | claimed |
| US-20050196418-A1 | Bioavailability and improved delivery of alkaline pharmaceutical drugs | YU RUEY J (US) | 2005-09-08 | — | — | US | claimed |
| US-20050171194-A1 | Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions | YU RUEY J (US) | 2005-08-04 | — | — | US | claimed |
| WO-2005055947-A2 | ENLARGEMENT OF MUCOCUTANEOUS OR CUTANEOUS ORGANS AND SITES WITH TOPICAL COMPOSITIONS | YU RUEY J (US) | 2005-06-23 | — | — | WO | claimed |
| US-20040214215-A1 | Bioavailability and improved delivery of alkaline pharmaceutical drugs | YU RUEY J (US) | 2004-10-28 | — | — | US | claimed |
| WO-2004080468-A1 | IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ALKALINE PHARMACEUTICAL DRUGS | YU RUEY J (US) | 2004-09-23 | — | — | WO | claimed |
| US-5686489-A | TOPICALLY APPLIED TO INDUCE GLYCOSAMINOGLYCAN, PROTEOGLYCAN, COLLAGEN AND ELASTIN BIOSYNTHESIS; WRINKLE RESISTANCE | TRISTRATA TECHNOLOGY, INC. (US) | 1997-11-11 | — | — | US | claimed |
| US-5621006-A | TOPICALLY APPLYING IN A VEHICLE, E.G. HYDROXYACIDS, KETOACIDS AND SALTS, ESTERS THEREOF | YU RUEY J (US) | 1997-04-15 | — | — | US | claimed |
| WO-1996040047-A1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 1996-12-19 | — | — | WO | claimed |
| US-5561157-A | INCLUDES ORGANIC ALPHA AND BETA HYDROXY OR KETO CARBOXYLIC ACIDS, ESTERS, LACTONES AND/OR SALTS; USED FOR SKIN DISORDERS | TRISTRATA INC (US) | 1996-10-01 | — | — | US | claimed |
| US-5561158-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA, INCORPORATED | 1996-10-01 | — | — | US | claimed |
| US-5554597-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554654-A | COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554652-A | TOPICALLY APPLYING MIXTURE TO REDUCE OR PREVENT SKIN DISORDERS | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| WO-1992018116-A1 | COMPOSITIONS COMPRISING 2-HYDROXYCARBOXYLIC ACIDS AND RELATED COMPOUNDS, AND METHODS FOR ALLEVIATING SIGNS OF DERMATOLOGICAL AGING | YU RUEY J (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0508324-A2 | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | Yu, Ruey J., Dr. (US) | 1992-10-14 | — | — | EP | claimed |