Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269915 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL4559573 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL3794261 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL4559570 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL3682579 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL4559828 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL4559831 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL3794524 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL1151027 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 | |
| SCHEMBL2020733 | 1.00 | EP300 (0.69) | EP300PPARGPPARATERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3422006-B1 | DETECTION OF RISK OF PRE-ECLAMPSIA | UNIV COLLEGE CORK NATIONAL UNIV OF IRELAND CORK (IE) | 2023-11-01 | — | — | EP | disclosed |
| WO-2021034771-A1 | SURROGATE OF VO2 MAX TEST | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |
| US-20190056380-A1 | DETECTION OF RISK OF PRE-ECLAMPSIA | UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2019-02-21 | — | — | US | disclosed |
| EP-3422006-A1 | DETECTION OF RISK OF PRE-ECLAMPSIA | University College Cork, National University of Ireland, Cork (IE) | 2019-01-02 | — | — | EP | disclosed |
| EP-3206033-A1 | DETECTION OF RISK OF PRE-ECLAMPSIA | University College Cork, National University of Ireland, Cork (IE) | 2017-08-16 | — | — | EP | disclosed |
| US-20160223517-A1 | DETECTION OF RISK OF PRE-ECLAMPSIA | UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2016-08-04 | — | — | US | disclosed |
| US-9262582-B2 | Detection of risk of pre-eclampsia | UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2016-02-16 | — | — | US | disclosed |
| US-20130073212-A1 | DETECTION OF RISK OF PRE-ECLAMPSIA | UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2013-03-21 | — | — | US | disclosed |
| WO-2013037872-A1 | LIQUID ACTIVE SUBSTANCE PREPARATIONS FOR FUNGICIDAL PROTECTION FROM COLLAGEN-FIBROUS SUBSTRATES | LANXESS DEUTSCHLAND GMBH (DE) | 2013-03-21 | — | — | WO | disclosed |
| EP-2517019-A1 | DETECTION OF RISK OF PRE-ECLAMPSIA | University College Cork, National University Of Irland Cork (IE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011080170-A9 | DETECTION OF RISK OF PRE-ECLAMPSIA | UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2012-07-12 | — | — | WO | disclosed |
| WO-2011080170-A1 | DETECTION OF RISK OF PRE-ECLAMPSIA | UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011075842-A1 | METABOLOMIC BIOMARKER SIGNATURE OF PRE-ECLAMPSIA RISK | KENNY LOUISE C (IE) | 2011-06-30 | — | — | WO | disclosed |
| US-20090209485-A1 | MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES | PARISH CHRISTOPHER RICHARD | 2009-08-20 | — | — | US | disclosed |
| EP-1871392-A1 | MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES | Parish, Christopher Richard (AU) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006102717-A1 | MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES | PARISH CHRISTOPHER RICHARD (AU) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209485-A1 | MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES | FLT4, UGGT1, FLT1 | EP300 2954/4885PPARG 1632/4885PPARA 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.