⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504771 | 0.97 | NPC1 (0.30) | — | |
| SCHEMBL27684502 | 0.85 | NPC1 (0.43) | — | |
| SCHEMBL6247258 | 0.83 | FAAH (0.43) | — | |
| SCHEMBL28133748 | 0.83 | — | — | |
| SCHEMBL26929262 | 0.81 | FAAH (0.41) | — | |
| SCHEMBL27881702 | 0.81 | FAAH (0.46) | — | |
| SCHEMBL3273225 | 0.80 | — | — | |
| SCHEMBL11197412 | 0.79 | — | — | |
| SCHEMBL1164814 | 0.78 | — | — | |
| SCHEMBL2486748 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103242341-A | Thieno 2,4-substituted pyrimidine compound, and pharmaceutical composition and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2013-08-14 | — | — | CN | claimed |
| US-10392559-B2 | Preparation method of nanocrystals coated with metal-surfactant layers | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-08-27 | — | — | US | disclosed |
| CN-103242341-B | Thieno-2,4 substituted pyrimidines compounds and pharmaceutical composition thereof and application | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-103242341-A | Thieno 2,4-substituted pyrimidine compound, and pharmaceutical composition and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2013-08-14 | — | — | CN | disclosed |
| US-20100159249-A1 | PREPARATION METHOD OF NANOCRYSTALS COATED WITH METAL-SURFACTANT LAYERS | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2010-06-24 | — | — | US | disclosed |
| CN-1123714-A | Amphoteric surfactants having multiple hydrophobic and hydrophilic groups | RHONE POULENC INC (US) | 1996-06-05 | — | — | CN | disclosed |