SCHEMBL3795378

SCHEMBL3795378

C=COC(=O)CC(Cl)CCl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5425444 0.80
SCHEMBL7577258 0.80 TDP1 (0.41) TP53TSHRTDP1
SCHEMBL27840050 0.77
SCHEMBL11417305 0.77
SCHEMBL27578015 0.75 LMNA (0.31)
SCHEMBL5246512 0.75
1,2,3-Trichloropropane SCHEMBL8932779 0.75 TDP1 (0.32) TP53TSHRTDP1
SCHEMBL19506901 0.75
SCHEMBL6154882 0.73 SLC22A6 (0.38)
SCHEMBL99769 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2209496-A2 MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES VANDERBILT UNIVERSITY (US) 2010-07-28 EP disclosed
WO-2009061854-A2 MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES VANDERBILT UNIVERSITY (US) 2009-05-14 WO disclosed
EP-0695830-B1 FORGERY-PROOF PAPER TOKUSHU PAPER MFG CO LTD (JP) 2002-07-24 EP disclosed