SCHEMBL379556

SCHEMBL379556

N#Cc1ccc(NN)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.55
CA2 P00918 5/20 0.54
CA1 P00915 4/20 0.54
CYP1B1 Q16678 1/20 0.47
LOXL2 Q9Y4K0 2/20 0.46
CA9 Q16790 4/20 0.46
CA12 O43570 3/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP2A6 P11509 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MMP2 P08253 1/20 0.45
LMNA P02545 4/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 2/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL20984185 0.97 IDO1 (0.53) IDO1CA2CA1CYP1B1LOXL2
Hydrochloric Acid SCHEMBL541642 0.97 IDO1 (0.53) IDO1CA2CA1CYP1B1LOXL2
Hydrazine SCHEMBL28385178 0.95 IDO1 (0.52) IDO1CA2CA1CYP1B1LOXL2
SCHEMBL11480587 0.87 IDO1 (0.46) IDO1CA2CA1CYP1B1LOXL2
Sulfuric Acid SCHEMBL20984569 0.87 CA1 (0.58) IDO1CA2CA1CA9CA12
Oxalic Acid SCHEMBL20984920 0.87 IDO1 (0.50) IDO1CA2CA1CA9CA12
Phosphoric Acid SCHEMBL20984774 0.87 MMP2 (0.59) IDO1CA2CA1CA9CA12
SCHEMBL11480582 0.87 IDO1 (0.46) IDO1CA2CA1CYP1B1LOXL2
Oxalic Acid SCHEMBL20984921 0.87 IDO1 (0.50) IDO1CA2CA1CA9CA12
SCHEMBL9529531 0.85 CA1 (0.56) IDO1CA2CA1CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019332-A 1, 5-Disubstituted-4-bromopyrazole compound and preparation method and application thereof 赣南师范大学 2024-11-26 CN claimed
CN-118930487-A 1,3, 5-Trisubstituted pyrazole compound and preparation method thereof 赣南师范大学 2024-11-12 CN claimed
CN-115124441-B Preparation method of No Bo Suan hydrazide compound, product and application thereof 南京林业大学 2024-04-02 CN claimed
CN-117700429-A Polyurethane chain extender, polyurethane prepolymer, electrochromic polyurethane adhesive and preparation method thereof 广州白云科技股份有限公司 2024-03-15 CN claimed
CN-117402076-A Preparation method of norbornenyl acid formylhydrazine compound, product and application thereof 南京林业大学 2024-01-16 CN claimed
CN-117049763-B Method for degrading sludge organic matters by wet oxidation technology 上海鸣桦环境科技有限公司 2023-12-22 CN claimed
CN-117049763-A Method for degrading sludge organic matters by wet oxidation technology 上海鸣桦环境科技有限公司 2023-11-14 CN claimed
CN-117024304-A Preparation method of N ', N' -diaryl hydrazide compound 赣南师范大学 2023-11-10 CN claimed
CN-110003160-B Osthole hydrazone/acylhydrazone/sulfonylhydrazone derivatives, and preparation method and application thereof 贵州中医药大学 2022-10-11 CN claimed
CN-115124441-A Preparation method of nopyl acid hydrazide compounds, nopyl acid hydrazide compounds and application of nopyl acid hydrazide compounds 南京林业大学 2022-09-30 CN claimed
US-20140005395-A1 4-(2-(6-SUBSTITUTED-HEXYLIDENE) HYDRAZINYL)BENZONITRILE AND PREPARATION THEREOF FOREST LABORATORIES HOLDINGS LIMITED (BM) 2014-01-02 US claimed
JP-4756740-B2 2011-08-24 JP claimed
US-7714151-B2 Aminated isoflavonoid derivatives and uses thereof NOVOGEN RESEARCH PTY LTD (AU) 2010-05-11 US claimed
CN-1807223-A Dynamic molecule base electron device based on hydrazine derived biological molecular material UNIV FUDAN (CN) 2006-07-26 CN claimed
CN-1200931-C Preparation method of R- (+) -6-formamido-3-N-methylamino-1, 2,3, 4-tetrahydrocarbazole FINARIS CO LTD (GB) 2005-05-11 CN claimed
US-6359146-B1 RESOLUTION OF ENANTIOMORPH MIXTURE VERNALIS LIMITED (GB) 2002-03-19 US claimed
EP-1070051-A1 PROCESS FOR THE PRODUCTION OF R-(+)-6- CARBOXAMIDO- 3-N- METHYLAMINO- 1,2,3,4- TETRAHYDROCARBAZOLE Vernalis Limited (GB) 2001-01-24 EP claimed
WO-1999054302-A1 PROCESS FOR THE PRODUCTION OF R-(+)-6- CARBOXAMIDO- 3-N- METHYLAMINO- 1,2,3,4- TETRAHYDROCARBAZOLE VERNALIS LIMITED (GB) 1999-10-28 WO claimed
EP-0370332-B1 N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants BAYER AG (DE) 1994-03-30 EP claimed
EP-0370332-A1 N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants BAYER AG (DE) 1990-05-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140005395-A1 4-(2-(6-SUBSTITUTED-HEXYLIDENE) HYDRAZINYL)BENZONITRILE AND PREPARATION THEREOF AVPR1B, AVPR2, AVPR1A IDO1 1689/4885CA2 1843/4885CA1 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.