Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | NT5E | P21589 | 3/20 | 0.33 |
| ▸ | CASP6 | P55212 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715904 | 0.98 | TDP1 (0.61) | TDP1LCKFYNING2TSHR | |
| SCHEMBL18289491 | 0.93 | TDP1 (0.61) | TDP1LCKFYNING2TSHR | |
| SCHEMBL11828630 | 0.84 | TDP1 (0.52) | TDP1LCKFYNING2TSHR | |
| SCHEMBL3195354 | 0.83 | TDP1 (0.47) | TDP1LCKFYNING2NT5E | |
| SCHEMBL11830502 | 0.81 | LCK (0.66) | TDP1LCKFYNING2TSHR | |
| SCHEMBL5013229 | 0.80 | LCK (0.55) | TDP1LCKFYNING2TSHR | |
| SCHEMBL124133 | 0.80 | LCK (0.55) | TDP1LCKFYNING2TSHR | |
| SCHEMBL313977 | 0.79 | TDP1 (0.57) | TDP1TSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19881180 | 0.79 | TDP1 (0.47) | TDP1LCKFYNLMNAGAA | |
| SCHEMBL6520071 | 0.79 | LCK (0.41) | TDP1LCKFYNING2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135167-A1 | COPOLYELECTROLYTE MONOMERS BEARING MULTIPLE ACID GROUPS | ARKEMA INC. (US) | 2010-11-25 | — | — | WO | claimed |