SCHEMBL6520071

SCHEMBL6520071

O=Cc1cc(S(=O)(=O)O)cc(S(=O)(=O)O)c1.[NaH].[NaH]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
ING2 Q9H160 1/20 0.40
TSHR P16473 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 1/20 0.36
ALDH1A1 P00352 4/20 0.34
NT5E P21589 3/20 0.34
HSD17B10 Q99714 3/20 0.34
CASP6 P55212 3/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PTGS2 P35354 1/20 0.33
RAB9A P51151 1/20 0.33
NSD2 O96028 2/20 0.32
GAA P10253 1/20 0.32
PLCG1 P19174 1/20 0.32
DNMT1 P26358 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28510700 1.00 LCK (0.41) LCKFYNTDP1ING2TSHR
SCHEMBL1199354 0.98 LCK (0.43) LCKFYNTDP1ING2TSHR
SCHEMBL18475662 0.93 LCK (0.43) LCKFYNTDP1ING2TSHR
SCHEMBL10931312 0.91 LCK (0.41) LCKFYNTDP1ING2TSHR
SCHEMBL10452211 0.86 ERN1 (0.36) LCKFYNTDP1ING2TSHR
SCHEMBL6553447 0.83 ERN1 (0.38) LCKFYNTDP1ING2TSHR
SCHEMBL124133 0.82 LCK (0.55) LCKFYNTDP1ING2TSHR
SCHEMBL5013229 0.82 LCK (0.55) LCKFYNTDP1ING2TSHR
SCHEMBL28526260 0.80 GAA (0.41) TDP1LMNAALDH1A1CASP6PTGS2
SCHEMBL3795605 0.79 TDP1 (0.59) LCKFYNTDP1ING2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739083-B2 Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt TERUMO KABUSHIKI KAISHA (JP) 2023-08-29 US disclosed
US-20210009578-A1 DISPOSABLE SENSOR CHIP WITH REAGENT INCLUDING 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT TERUMO KABUSHIKI KAISHA (JP) 2021-01-14 US disclosed
US-10851094-B2 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt, reagent for biological component concentration measurement containing said salt, and biological component concentration measurement method using said salt TERUMO KABUSHIKI KAISHA (JP) 2020-12-01 US disclosed
EP-3514156-A1 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT, BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT REAGENT CONTAINING SAID SALT, AND BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT METHOD USING SAID SALT Terumo Kabushiki Kaisha (JP) 2019-07-24 EP disclosed
US-20190185465-A1 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT, REAGENT FOR BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT CONTAINING SAID SALT, AND BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT METHOD USING SAID SALT TERUMO KABUSHIKI KAISHA (JP) 2019-06-20 US disclosed
CN-109689648-A 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt, reagent for measuring concentration of biological component containing the salt, and method for measuring concentration of biological component using the salt 泰尔茂株式会社 2019-04-26 CN disclosed
US-20050048554-A1 Method of making and using hybrid polymeric thin films for bio-microarray applications ENGERY, UNITED STATES DEPARTMENT OF 2005-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210009578-A1 DISPOSABLE SENSOR CHIP WITH REAGENT INCLUDING 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT STUB1, BTK, TST LCK 133/4885FYN 1421/4885TDP1 2299/4885
US-10851094-B2 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt, reagent for biological component concentration measurement containing said salt, and biological component concentration measurement method using said salt BPNT1, EPB41, IL4 LCK 2664/4885FYN 3827/4885TDP1 3057/4885
US-11739083-B2 Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt STUB1, BTK, TST LCK 133/4885FYN 1421/4885TDP1 2299/4885
US-20190185465-A1 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT, REAGENT FOR BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT CONTAINING SAID SALT, AND BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT METHOD USING SAID SALT BPNT1, EPB41, IL4 LCK 2664/4885FYN 3827/4885TDP1 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.