Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.33 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174801 | 0.82 | LMNA (0.42) | LMNAPTPN1ACP1CDC25BTSHR | |
| SCHEMBL13269123 | 0.80 | PTPN1 (0.35) | LMNAPTPN1ACP1CDC25B | |
| SCHEMBL30791475 | 0.80 | PTPN1 (0.35) | LMNAPTPN1ACP1CDC25B | |
| SCHEMBL16174694 | 0.79 | PTPN1 (0.33) | LMNAPTPN1ACP1CDC25BTSHR | |
| SCHEMBL16174854 | 0.79 | LMNA (0.44) | LMNAPTPN1CDC25BELANE | |
| SCHEMBL16174837 | 0.78 | ELANE (0.51) | LMNAELANE | |
| SCHEMBL16175041 | 0.77 | PTPN1 (0.40) | LMNAPTPN1ACP1CDC25BKDM4E | |
| SCHEMBL3813021 | 0.75 | PTPN1 (0.39) | LMNAPTPN1ACP1CDC25BKDM4E | |
| SCHEMBL11620537 | 0.75 | LMNA (0.32) | LMNA | |
| SCHEMBL22733768 | 0.75 | LMNA (0.43) | LMNAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6009385-A | — | — | None | — | — | JP | disclosed |
| WO-2024038378-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2024-02-22 | — | — | WO | disclosed |
| CN-116601158-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-9611410-B2 | Adhesive resin composition, laminate, and self-stripping method | MITSUI CHEMICALS TOHCELLO, INC. (JP) | 2017-04-04 | — | — | US | disclosed |
| US-20140322474-A1 | ADHESIVE RESIN COMPOSITION, LAMINATE, AND SELF-STRIPPING METHOD | MITSUI CHEMICALS TOHCELLO, INC. (JP) | 2014-10-30 | — | — | US | disclosed |
| EP-2792725-A1 | ADHESIVE RESIN COMPOSITION, LAMINATE BODY, AND SELF-PEELING METHOD | Mitsui Chemicals Tohcello Co., Ltd. (JP) | 2014-10-22 | — | — | EP | disclosed |
| US-20130053553-A1 | HETEROCYCLIC COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-02-28 | — | — | US | disclosed |
| US-8232275-B2 | 2,2-bis-(hydroxymethyl)cyclopropylidenemethyl-purines and -pyrimidines as antiviral agents | WAYNE STATE UNIVERSITY (US) | 2012-07-31 | — | — | US | disclosed |
| EP-2280974-B1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |
| US-20110275652-A1 | 2,2-BIS-(HYDROXYMETHYL)CYCLOPROPYLIDENEMETHYL-PURINES AND -PYRIMIDINES AS ANTIVIRAL AGENTS | WAYNE STATE UNIVERSITY | 2011-11-10 | — | — | US | disclosed |
| US-4110368-A | PROSTAGLANDINS, BRONCHODILATOR, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4074056-A | ANTIMICROBIAL, HYPOTENSIVE, AND ANTIULCER AGENTS, INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4061672-A | Derivatives of 9-hydroxy-13-trans-prostenoic acid | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4060540-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-RE29469-E | PROSTAGLANDINS; BRONCHODILATORS, HYPOTENSIVES, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-4018811-A | MICROBIOCIDES, ANTIULCER, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4007210-A | PROSTANOIC ACID DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-3966773-A | BRONCHODILATOR, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3950406-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-04-13 | — | — | US | disclosed |
| US-3932479-A | BRONCHODILATOR, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275652-A1 | 2,2-BIS-(HYDROXYMETHYL)CYCLOPROPYLIDENEMETHYL-PURINES AND -PYRIMIDINES AS ANTIVIRAL AGENTS | TPMT, HPRT1, MTAP | LMNA 4101/4885PTPN1 2883/4885ACP1 4112/4885 |
| US-20130053553-A1 | HETEROCYCLIC COMPOUNDS | CYP2C8, UGT1A8, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | LMNA 1566/4885PTPN1 4414/4885ACP1 3473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.