Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Doxofylline SCHEMBL5964475 | 1.00 | KMT2A (1.00) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| Doxofylline SCHEMBL27949428 | 0.99 | KMT2A (0.97) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| Doxofylline SCHEMBL27924903 | 0.99 | KMT2A (0.97) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| Doxofylline SCHEMBL27934328 | 0.99 | KMT2A (0.97) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| Doxofylline SCHEMBL27934338 | 0.99 | KMT2A (0.97) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL9293404 | 0.85 | KMT2A (0.74) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL22481954 | 0.84 | KMT2A (0.73) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL18256126 | 0.82 | KMT2A (0.69) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL18256137 | 0.80 | KMT2A (0.66) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL29006028 | 0.80 | KMT2A (0.66) | KMT2AADORA2BLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3377 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250213647-A1 | CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE | UNIVERSITY OF SOUTH FLORIDA | 2025-07-03 | — | — | US | claimed |
| CN-114264730-B | Method for detecting related substances of doxofylline injection | 扬子江药业集团南京海陵药业有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119954729-A | Method for preparing deuterated aza-arene by heterogeneous photocatalytic hydrogen-deuterium exchange | 中国科学技术大学苏州高等研究院 | 2025-05-09 | — | — | CN | claimed |
| CN-119909028-A | Doxofylline tablet and preparation method thereof | 福安药业集团宁波天衡制药有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119798303-A | UV (ultraviolet) photo-curing powder treating agent and preparation method and application thereof | 苏州高泰电子技术股份有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119432743-A | Kit for inducing stem cells to differentiate into motor nerve precursor cells and/or motor neurons and application of kit | 士泽生物医药（苏州）有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119423119-A | Soil additive for improving soil quality and preparation method thereof | 菏泽市农业科学院(山东省农业科学院菏泽市分院) | 2025-02-14 | — | — | CN | claimed |
| CN-118576571-B | Oral film with customizable drug release curve and preparation method thereof | 浙江大学 | 2025-02-14 | — | — | CN | claimed |
| US-20250049770-A1 | Phosphodiesterase 4 Inhibitor Decreases Thrombosis in Simulated ECMO Model | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2025-02-13 | — | — | US | claimed |
| CN-119351306-A | Method for promoting differentiation of thymic epithelial cells and thymic epithelial cell progenitors of pluripotent stem cells | 纽约市哥伦比亚大学理事会 | 2025-01-24 | — | — | CN | claimed |
| WO-2000012076-A1 | NITROSATED AND NITROSYLATED PHOSPHODIESTERASE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2000-03-09 | — | — | WO | claimed |
| EP-0954292-A1 | PHARMACEUTICAL FORMULATIONS WITH DELAYED DRUG RELEASE | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1999-11-10 | — | — | EP | claimed |
| CN-1044810-C | Synthetic process of new drug dosotheophylline | SHANGHAI INST ORGANIC CHEM (CN) | 1999-08-25 | — | — | CN | claimed |
| CN-1041728-C | Synthsis of doxofylline | HUAXING PHARMACEUTICAL CO LTD (CN) | 1999-01-20 | — | — | CN | claimed |
| US-5788987-A | TIME-SPECIFIC CONTROLLED RELEASE DOSAGE FORMULATION | POLI INDUSTRIA CHIMICA SPA (IT) | 1998-08-04 | — | — | US | claimed |
| WO-1998032425-A1 | PHARMACEUTICAL FORMULATIONS WITH DELAYED DRUG RELEASE | POLI INDUSTRIA CHIMICA S.P.A. (US) | 1998-07-30 | — | — | WO | claimed |
| WO-1998030900-A2 | SCREENING METHOD FOR COMPOUNDS ACTIVE IN TREATING MYOPIA AND HYPERMETROPIA | KLAUS TRIER APS (DK) | 1998-07-16 | — | — | WO | claimed |
| CN-1160715-A | Synthsis of doxofylline | HUAXING PHARMACEUTICAL CO LTD (CN) | 1997-10-01 | — | — | CN | claimed |
| CN-1133842-A | Preparation method of doxofylline | SHAOXING MEDICINAL INDUSTRY IN (CN) | 1996-10-23 | — | — | CN | claimed |
| CN-1106404-A | Synthetic process of new drug dosotheophylline | SHANGHAI INST ORGANIC CHEM (CN) | 1995-08-09 | — | — | CN | claimed |