SCHEMBL379642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4954711	0.97	CLK4 (0.49)	CLK4DGAT2TUBB4ATUBBTUBA3C
	SCHEMBL379675	0.87	TUBB4A (0.45)	CLK4TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL379615	0.84	CLK4 (0.53)	CLK4TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL379643	0.84	CYP1A2 (0.58)	CLK4CCNCCDK8CYP1A2CYP3A4
	SCHEMBL4952460	0.82	CLK4 (0.52)	CLK4TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL379868	0.82	TUBB4A (0.45)	CLK4TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL379480	0.81	CYP1A2 (0.63)	CLK4CCNCCDK8CYP1A2CYP3A4
	SCHEMBL380352	0.80	HSD17B10 (0.48)	CLK4CCNCCDK8CYP1A2CYP3A4
	SCHEMBL379638	0.78	TUBB4A (0.44)	CLK4TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL379896	0.76	CLK4 (0.59)	CLK4CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.