SCHEMBL3796497

SCHEMBL3796497

CCCCCCCCCCCCCCCCCC(=O)OC1CC(C)(C)N(C(C)=O)C(C)(C)C1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.55
DGKA P23743 1/20 0.40
PRKCA P17252 6/20 0.39
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PAM P19021 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527560 0.94 NAAA (0.45) NAAASMN1; SMN2
SCHEMBL5491857 0.93 NAAA (0.42) NAAASMN1; SMN2
SCHEMBL12919729 0.90 NAAA (0.39) NAAASMN1; SMN2
SCHEMBL13240546 0.86 NAAA (0.39) NAAASMN1; SMN2
SCHEMBL11178840 0.86 NAAA (0.51) NAAADGKAPRKCA
SCHEMBL2221561 0.85 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL225069 0.85 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL13075208 0.85 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL17296568 0.85 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2
SCHEMBL15300079 0.85 NAAA (0.58) NAAADGKAPRKCALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4957953-A MONO-AND POLYTETRAMETHYLPIPERIDINE ESTERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US claimed
WO-2010056452-A2 DIMERIC CYANOACRYLATE COMPOUNDS AS RED-SHIFTED UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2010-05-20 WO disclosed
US-4957953-A MONO-AND POLYTETRAMETHYLPIPERIDINE ESTERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed
EP-0052073-A1 Light stabilization of acid catalysed storing enamels CIBA-GEIGY AG (CH) 1982-05-19 EP disclosed