Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057214 | 1.00 | TSHR (0.44) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL4770420 | 0.97 | TSHR (0.39) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL16497225 | 0.94 | TSHR (0.37) | TSHRTHRBLMNASLC22A1 | |
| SCHEMBL27888186 | 0.90 | TSHR (0.40) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL6303358 | 0.89 | TSHR (0.44) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL339790 | 0.88 | TSHR (0.35) | TSHRTHRBLMNA | |
| SCHEMBL9238298 | 0.86 | TSHR (0.35) | TSHRTHRBLMNA | |
| SCHEMBL3481918 | 0.83 | TSHR (0.32) | TSHRTHRBLMNA | |
| SCHEMBL6297160 | 0.80 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL16496779 | 0.79 | OPRM1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100012880-A1 | MAGNETIC PARTICLES AND METHODS OF MAKING AND USING THE SAME | COLUMBUS NANOWORKS, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| EP-2062271-A2 | MAGNETIC PARTICLES AND METHODS OF MAKING AND USING THE SAME | Columbus Nanoworks, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008030862-A2 | MAGNETIC PARTICLES AND METHODS OF MAKING AND USING THE SAME | COLUMBUS NANOWORKS, INC. (US) | 2008-03-13 | — | — | WO | disclosed |