Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246768 | 0.92 | DPP4 (0.42) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL1246765 | 0.92 | DPP4 (0.42) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2182440 | 0.90 | DPP4 (0.52) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL3055324 | 0.87 | DPP4 (0.44) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8760014 | 0.84 | ACE (0.53) | ACE | |
| SCHEMBL8760024 | 0.84 | ACE (0.53) | ACE | |
| SCHEMBL10782979 | 0.84 | ACE (0.53) | ACE | |
| SCHEMBL10783008 | 0.84 | ACE (0.53) | ACE | |
| SCHEMBL9450511 | 0.84 | DPP4 (0.45) | DPP4DPP7DPP8DPP9ITGB3 | |
| SCHEMBL2182382 | 0.83 | DPP7 (0.52) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235038-A1 | PEPTIDE COMBINATION | GKL-Biotec AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| WO-2010075849-A1 | PEPTIDE COMBINATION | GKL-BIOTEC AG (CH) | 2010-07-08 | — | — | WO | disclosed |
| WO-2007090022-A2 | NOVEL COMPOUNDS FOR TARGETING ENDOTHELIAL CELLS, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THEIR USE | BRACCO INTERNATIONAL B.V. (NL) | 2007-08-09 | — | — | WO | disclosed |