Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.52 |
| ▸ | DPP4 | P27487 | 5/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196112 | 0.86 | DPP4 (0.41) | DPP7DPP4DPP8DPP9ACE | |
| SCHEMBL2182440 | 0.86 | DPP4 (0.52) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL2195632 | 0.85 | DPP7 (0.48) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL3796746 | 0.83 | DPP4 (0.49) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL9450527 | 0.82 | OPRK1 (0.54) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL9450511 | 0.80 | DPP4 (0.45) | DPP7DPP4DPP8DPP9ACE | |
| SCHEMBL8852004 | 0.79 | DPP7 (0.78) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL2182868 | 0.79 | DPP7 (0.78) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL4956097 | 0.79 | DPP7 (0.78) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL29666885 | 0.79 | ACE (0.49) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | DPP7 450/4885DPP4 525/4885DPP8 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.