Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 13/20 | 0.43 |
| ▸ | NAMPT | P43490 | 6/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787257 | 0.90 | DDR1 (0.39) | DDR1NAMPTEPHX2 | |
| SCHEMBL3788739 | 0.88 | DDR1 (0.37) | DDR1NAMPT | |
| SCHEMBL3787856 | 0.87 | NAMPT (0.38) | DDR1NAMPT | |
| SCHEMBL3710884 | 0.87 | EPHX2 (0.47) | DDR1EPHX2 | |
| SCHEMBL3785014 | 0.86 | DDR1 (0.46) | DDR1NAMPT | |
| SCHEMBL3810011 | 0.85 | EPHX2 (0.49) | EPHX2 | |
| SCHEMBL3792501 | 0.85 | CNR2 (0.48) | EPHX2 | |
| SCHEMBL3810168 | 0.85 | CD274 (0.42) | DDR1EPHX2 | |
| SCHEMBL3789474 | 0.80 | DDR1 (0.41) | DDR1NAMPT | |
| SCHEMBL3788311 | 0.80 | DDR1 (0.40) | DDR1NAMPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |