Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827613 | 0.88 | AKR1C3 (0.56) | AKR1C3AKR1C2AKR1C1PTGS1UGT2B7 | |
| SCHEMBL2318137 | 0.85 | AKR1C3 (0.69) | AKR1C3AKR1C2AKR1C1PTGS1UGT2B7 | |
| SCHEMBL27734602 | 0.81 | AKR1C3 (0.52) | AKR1C3AKR1C2AKR1C1PTGS1UGT2B7 | |
| SCHEMBL10418910 | 0.81 | AOC3 (0.48) | AKR1C3AKR1C2AKR1C1PTGS1UGT2B7 | |
| SCHEMBL28605610 | 0.81 | EPHX1 (0.68) | PTGS1UGT2B7EPHX1TNFSLC6A2 | |
| SCHEMBL10418907 | 0.81 | AOC3 (0.48) | AKR1C3AKR1C2AKR1C1PTGS1UGT2B7 | |
| SCHEMBL16634905 | 0.80 | ROCK2 (0.52) | AKR1C3AKR1C2AKR1C1PTGS1 | |
| Fenbutyramide SCHEMBL1478462 | 0.78 | EPHX1 (0.63) | EPHX1MEN1KMT2A | |
| Fenbutyramide SCHEMBL232920 | 0.78 | EPHX1 (0.63) | EPHX1MEN1KMT2A | |
| SCHEMBL5716820 | 0.78 | UGT2B7 (0.53) | UGT2B7EPHX1AOC3TNFMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911645-A1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | Université de Lille (FR) | 2021-11-24 | — | — | EP | claimed |
| WO-2020148403-A1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIVERSITE DE LILLE (FR) | 2020-07-23 | — | — | WO | claimed |
| US-20190263775-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES | BIOMARIN PHARM INC (US) | 2019-08-29 | — | — | US | claimed |
| CN-108569977-A | A kind of preparation method of primary fatty amides | 中国科学技术大学 | 2018-09-25 | — | — | CN | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263775-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES | GBA1, UGCG, GBA2 | AKR1C3 1409/4885AKR1C2 1225/4885AKR1C1 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.