Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | BMI1 | P35226 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792099 | 0.91 | HSD17B10 (0.44) | ALDH1A1L3MBTL1POLBTDP1SORT1 | |
| SCHEMBL1708022 | 0.88 | ALDH1A1 (0.48) | ALDH1A1POLBSORT1DHODHTP53 | |
| SCHEMBL1708275 | 0.81 | BMI1 (0.37) | ALDH1A1L3MBTL1DHODHBMI1 | |
| SCHEMBL1708107 | 0.79 | TSHR (0.46) | ALDH1A1POLBTP53MRGPRX4MYC | |
| SCHEMBL1708108 | 0.72 | POLB (0.53) | ALDH1A1L3MBTL1POLBTP53MYC | |
| SCHEMBL28464972 | 0.71 | TSHR (0.67) | ALDH1A1L3MBTL1POLBTP53 | |
| SCHEMBL1356522 | 0.69 | HSD17B10 (0.64) | ALDH1A1L3MBTL1POLBTDP1NOTUM | |
| SCHEMBL27715912 | 0.68 | TRPV1 (0.46) | ALDH1A1SORT1NOTUMTAS2R14MRGPRX4 | |
| SCHEMBL12135484 | 0.67 | KMT2A (0.50) | ALDH1A1L3MBTL1POLBTDP1DHODH | |
| SCHEMBL15727582 | 0.67 | KDM4E (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |