Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28282689 | 1.00 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL8750161 | 1.00 | — | — | |
| Piperazine SCHEMBL28418809 | 1.00 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL28015401 | 1.00 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL580602 | 1.00 | HIF1A (0.86) | — | |
| Water SCHEMBL28941037 | 1.00 | HIF1A (0.86) | — | |
| Hydrochloric Acid SCHEMBL28472109 | 0.94 | HIF1A (0.75) | — | |
| Hydrochloric Acid SCHEMBL28465717 | 0.94 | HIF1A (0.75) | — | |
| Piperazine SCHEMBL28525307 | 0.94 | HIF1A (0.75) | — | |
| Piperazine SCHEMBL10439207 | 0.94 | HIF1A (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12226756-B2 | Catalyst system and method for its preparation | RELIANCE INDUSTRIES LIMITED (IN) | 2025-02-18 | — | — | US | claimed |
| CN-118512927-A | PEODT conductive nanofiltration membrane, preparation method and cleaning method thereof | 南京工业大学 | 2024-08-20 | — | — | CN | claimed |
| CN-118161994-A | PEODT conductive nanofiltration membrane, preparation method and cleaning method thereof | 南京工业大学 | 2024-06-11 | — | — | CN | claimed |
| CN-112920315-B | pH sensing fluorescent polymer and preparation method and application thereof | 五邑大学 | 2022-11-15 | — | — | CN | claimed |
| US-20220339608-A1 | A CATALYST SYSTEM AND METHOD FOR ITS PREPARATION | RELIANCE INDUSTRIES LIMITED (IN) | 2022-10-27 | — | — | US | claimed |
| EP-3997196-A1 | A CATALYST SYSTEM AND METHOD FOR ITS PREPARATION | Reliance Industries Limited (IN) | 2022-05-18 | — | — | EP | claimed |
| CN-112920315-A | pH sensing fluorescent polymer and preparation method and application thereof | 五邑大学 | 2021-06-08 | — | — | CN | claimed |
| WO-2021038436-A1 | A CATALYST SYSTEM AND METHOD FOR ITS PREPARATION | RELIANCE INDUSTRIES LIMITED (IN) | 2021-03-04 | — | — | WO | claimed |
| CN-109228550-B | Composite fabric, preparation method thereof and automotive interior fabric based on composite fabric | 晟合新材料科技（嘉善）有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-106064096-B | Multi-metal catalyst system and its use in the production of upgraded fuels from biomass | 信实工业公司 | 2020-10-16 | — | — | CN | claimed |
| US-20020055448-A1 | Wetting agents for concrete cleaning and adhesives | U.S. BANK NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2002-05-09 | — | — | US | claimed |
| US-5948837-A | MIXTURE OF ORGANONITROGEN COMPOUND, PHOSPHOROUS PENTAOXIDE AND WATER | MONTELL NORTH AMERICA INC. (US) | 1999-09-07 | — | — | US | claimed |
| EP-0849260-A1 | Process for the production of flame retarding additives for polymer compositions, and products thereof | Montell North America Inc. (US) | 1998-06-24 | — | — | EP | claimed |
| US-5762650-A | Biocide plus surfactant for protecting carpets | OLIN CORPORATION (US) | 1998-06-09 | — | — | US | claimed |
| CN-1167618-A | Anti-beta-lactamase antibiotic composition | WEI ERMAN PHARMACEUTIC CO LTD (CN) | 1997-12-17 | — | — | CN | claimed |
| US-5656683-A | PIPERAZINE OR PIPERAZINONE-SUBSTITUTED ORGANOSULFONATE WETTING/LEVELING AGENT AND SURFACTANT OF ALCOHOL ALCOHOLATE AND/OR ORGANIC OR INORGANIC SALTS OF POLYCARBOXYLATED ALCOHOL ALCOHOLATES | OLIN CORPORATION (US) | 1997-08-12 | — | — | US | claimed |
| WO-1996011974-A1 | WETTING AGENTS FOR CONCRETE CLEANING AND ADHESIVES | OLIN CORPORATION (US) | 1996-04-25 | — | — | WO | claimed |
| US-5507867-A | CONTAINS PIPERAZINE-SUBSTITUTED ORGANOSULFONATES AND/OR PIPERAZINONE-SUBSTITUTED ORGANOSULFONATES WITH A POLYCARBOXYLATED ALCOHOL ALKOXYLATE | OLIN CORPORATION (US) | 1996-04-16 | — | — | US | claimed |
| US-5451238-A | Dye-leveling and cleaning composition containing an aqueous organic sulfonate plus an alcohol alkoxylate diluent | OLIN CORPORATION (US) | 1995-09-19 | — | — | US | claimed |
| US-5360457-A | Enhanced wetting, low-foaming, dye-leveling agent comprising a piperazine substituted organosulfonate | OLIN CORPORATION (US) | 1994-11-01 | — | — | US | claimed |