Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.58 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798341 | 0.85 | ACACB (0.61) | ACACBREV1 | |
| SCHEMBL3721683 | 0.84 | ACACB (0.60) | ACACB | |
| SCHEMBL3730360 | 0.81 | ACACB (0.66) | ACACB | |
| SCHEMBL3721682 | 0.81 | ACACB (0.66) | ACACB | |
| SCHEMBL23774182 | 0.80 | ACACB (0.66) | ACACB | |
| SCHEMBL17585131 | 0.79 | ACACB (0.72) | ACACB | |
| SCHEMBL23774228 | 0.77 | ACACB (0.67) | ACACB | |
| SCHEMBL23774152 | 0.76 | ACACB (0.74) | ACACB | |
| SCHEMBL3734290 | 0.76 | ACACB (0.90) | ACACB | |
| SCHEMBL17585128 | 0.75 | ACACB (0.73) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |