SCHEMBL3721682

SCHEMBL3721682

CC(=O)c1ccc2c(c1)CCN(Cc1ccc(OCC3CC3)cc1)C2

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACACB O00763 17/20 0.66
MCHR1 Q99705 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3798341 0.84 ACACB (0.61) ACACB
SCHEMBL23774152 0.83 ACACB (0.74) ACACB
SCHEMBL3721683 0.83 ACACB (0.60) ACACB
SCHEMBL3734290 0.82 ACACB (0.90) ACACB
SCHEMBL3798337 0.81 ACACB (0.58) ACACB
SCHEMBL17585236 0.80 ACACB (1.00) ACACB
SCHEMBL3725624 0.80 ITGB3 (0.53) ACACBMCHR1
SCHEMBL3730360 0.79 ACACB (0.66) ACACB
SCHEMBL3740226 0.79 ACACB (0.76) ACACB
SCHEMBL23774182 0.79 ACACB (0.66) ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010127212-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2010-11-04 WO disclosed
US-20100280067-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE SARMA PAKALA KUMARA SAVITHRU 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100280067-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE ACACA, ACACB, PC ACACB 2/4885MCHR1 4735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.