SCHEMBL379840

SCHEMBL379840

COC(=O)C(C)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2534589 1.00
SCHEMBL1140621 1.00
SCHEMBL30416229 0.97
Zinc Ion SCHEMBL29636397 0.97
SCHEMBL19638051 0.97
SCHEMBL31128663 0.82 ACACB (0.33)
SCHEMBL14076415 0.81 SMN1; SMN2 (0.37)
SCHEMBL1007906 0.80
SCHEMBL4144141 0.79 ALDH1A1 (0.33)
SCHEMBL24072865 0.78 SMN1; SMN2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110467617-A A kind of technique of three innovations synthesis 2- amino -5- methyl -4- oxo -3- n-propyl triazolo pyrimidine MENG XIANFENG 2019-11-19 CN claimed
US-20240417388-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-12-19 US disclosed
EP-4458916-A1 PHOTOCATALYTICALLY ACTIVE COATING COMPOSITION, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF TriOptoTec GmbH (DE) 2024-11-06 EP disclosed
US-12110286-B2 Benzimidazolone derived inhibitors of BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2024-10-08 US disclosed
CN-118561812-A Benzimidazolone-derived BCL6 inhibitors 癌症研究科技有限公司 2024-08-30 CN disclosed
WO-2024175026-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICAL USE THEREOF 哈尔滨三联药业股份有限公司 2024-08-29 WO disclosed
CN-118546109-A Nitrogen-containing heterocyclic compound and medical application thereof 哈尔滨三联药业股份有限公司 2024-08-27 CN disclosed
EP-4374858-A2 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 Cancer Research Technology Limited (GB) 2024-05-29 EP disclosed
EP-3630291-B9 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-05-29 EP disclosed
CN-111163839-B Benzimidazolone-derived BCL6 inhibitors 癌症研究科技有限公司 2024-05-28 CN disclosed
US-5508294-A USED TO TREAT HIV INFECTION G.D. SEARLE & CO. (US) 1996-04-16 US disclosed
CN-1031239-C Pesticide composition and application thereof SHELL INT RESEARCH (NL) 1996-03-13 CN disclosed
US-5470984-A Insecticides, molluscicides SHELL RESEARCH LIMITED (GB) 1995-11-28 US disclosed
EP-0666843-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFAMIC ACIDS USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1995-08-16 EP disclosed
EP-0656888-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1995-06-14 EP disclosed
WO-1994010136-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFAMIC ACIDS USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1994-05-11 WO disclosed
WO-1994004493-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1994-03-03 WO disclosed
EP-0213718-B1 1-DIMETHYLCARBAMOYL-3-SUBSTITUTED-5-SUBSTITUTED-1H-1,2,4-TRIAZOLES ROHM AND HAAS COMPANY (US) 1991-06-12 EP disclosed
CN-86105384-A 1-dimethylcarbamoyl-3-substituted-1H-1, 2, 4-triazoles 1987-04-08 CN disclosed
EP-0213718-A2 1-Dimethylcarbamoyl-3-substituted-5-substituted-1H-1,2,4-triazoles ROHM AND HAAS COMPANY (US) 1987-03-11 EP disclosed