Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.41 |
| ▸ | ACACA | Q13085 | 5/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076469 | 0.85 | ACACB (0.45) | ACACBACACASCN9A | |
| SCHEMBL3720740 | 0.84 | ACACB (0.47) | ACACBACACASCN9A | |
| SCHEMBL3722662 | 0.84 | ACACB (0.47) | ACACBACACASCN9A | |
| SCHEMBL3720867 | 0.84 | ACACB (0.49) | ACACBACACASCN9A | |
| Hydrochloric Acid SCHEMBL3722698 | 0.82 | ACACB (0.46) | ACACBACACASCN9A | |
| SCHEMBL3727054 | 0.81 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL13076378 | 0.80 | ACACB (0.44) | ACACBACACASCN9AALDH1A1MAPT | |
| SCHEMBL3728872 | 0.80 | ACACB (0.49) | ACACBACACA | |
| SCHEMBL3720735 | 0.79 | ACACB (0.48) | ACACBACACASCN9A | |
| SCHEMBL13076818 | 0.78 | ACACB (0.43) | ACACBACACASCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |