Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801572 | 0.83 | THRB (0.33) | PRMT1PRMT6 | |
| SCHEMBL3794126 | 0.74 | PRMT1 (0.36) | PRMT1PRMT6 | |
| SCHEMBL24174316 | 0.71 | MEN1 (0.31) | — | |
| SCHEMBL15203950 | 0.67 | KCNH2 (0.36) | — | |
| SCHEMBL15203664 | 0.67 | MEN1 (0.31) | — | |
| SCHEMBL23664362 | 0.67 | MEN1 (0.31) | PRMT1PRMT6 | |
| SCHEMBL23930444 | 0.65 | MEN1 (0.37) | — | |
| SCHEMBL22275416 | 0.64 | PRMT1 (0.35) | PRMT1PRMT6 | |
| SCHEMBL22275415 | 0.64 | THRB (0.33) | PRMT1PRMT6 | |
| SCHEMBL24173221 | 0.62 | PRMT1 (0.35) | PRMT1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |