Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TKT | P29401 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660440 | 0.84 | GAA (0.59) | GAATKT | |
| SCHEMBL19635567 | 0.79 | CSNK2A1 (0.33) | GAAIDO1 | |
| SCHEMBL3797314 | 0.78 | GAA (0.44) | GAATKT | |
| SCHEMBL26945695 | 0.77 | GAA (0.38) | GAAIDO1 | |
| SCHEMBL23398385 | 0.73 | GAA (0.38) | GAA | |
| SCHEMBL2612158 | 0.72 | GAA (0.40) | GAA | |
| SCHEMBL27140462 | 0.71 | GAA (0.41) | GAA | |
| SCHEMBL3799251 | 0.71 | GAA (0.33) | GAA | |
| SCHEMBL972895 | 0.71 | CYP2C9 (0.39) | GAA | |
| SCHEMBL19615346 | 0.71 | GAA (0.37) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |