SCHEMBL972895

SCHEMBL972895

CCc1nn(C)c(CO)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.39
GFER P55789 1/20 0.39
GAA P10253 1/20 0.37
NR3C1 P04150 2/20 0.32
LMNA P02545 2/20 0.32
MAPK8 P45983 1/20 0.32
MAPK9 P45984 1/20 0.32
MAPK10 P53779 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12871626 0.85 CYP2C9 (0.41) CYP2C9GFERGAANR3C1LMNA
SCHEMBL971293 0.82 CYP2C9 (0.40) CYP2C9GFERGAANR3C1LMNA
SCHEMBL28139455 0.80 CYP2C9 (0.39) CYP2C9GFERGAA
SCHEMBL31206423 0.76 GAA (0.37) GAA
SCHEMBL19615346 0.76 GAA (0.37) GAA
SCHEMBL13184316 0.75 KDM4E (0.46) GAALMNARAB9A
SCHEMBL32686853 0.73 ADCY10 (0.30)
SCHEMBL32686744 0.73 ADCY10 (0.30)
SCHEMBL12871802 0.72 GAA (0.45) CYP2C9GFERGAANR3C1LMNA
SCHEMBL7838461 0.71 GAA (0.59) CYP2C9GFERGAANR3C1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102007103-A Substituted sulfonic acid amide compounds BASF SE 2011-04-06 CN disclosed
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds BASF SE (DE) 2011-01-20 US disclosed
EP-2252590-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2010-11-24 EP disclosed
WO-2009101082-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2009-08-20 WO disclosed
CN-101362720-A Pyrazole methanol esters compounds, preparation method and application thereof JIANGSU PESTICIDE RES INST CO (CN) 2009-02-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds STS, NAPA, NAAA CYP2C9 647/4885GFER 59/4885GAA 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.