Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379890 | 0.95 | MAPK14 (0.80) | MAPK14MAPK13 | |
| SCHEMBL380784 | 0.92 | MAPK13 (0.80) | MAPK14MAPK13 | |
| SCHEMBL380115 | 0.91 | MAPK13 (0.81) | MAPK14MAPK13 | |
| SCHEMBL380368 | 0.90 | MAPK14 (0.93) | MAPK14MAPK13 | |
| SCHEMBL379880 | 0.90 | MAPK13 (0.84) | MAPK14MAPK13 | |
| SCHEMBL380485 | 0.89 | MAPK13 (0.84) | MAPK14MAPK13 | |
| SCHEMBL3614569 | 0.87 | MAPK13 (0.80) | MAPK14MAPK13 | |
| SCHEMBL379990 | 0.86 | MAPK14 (1.00) | MAPK14MAPK13 | |
| SCHEMBL3621253 | 0.85 | MAPK13 (1.00) | MAPK14MAPK13 | |
| SCHEMBL3620907 | 0.85 | MAPK13 (0.75) | MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086973-B1 | IMIDAZO- AND TRIAZOLO-PYRIDINE COMPOUNDS AND METHODS OF USE THEROF | AMGEN INC (US) | 2012-01-25 | — | — | EP | disclosed |