Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647647 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22HDAC11 | |
| SCHEMBL3330553 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22HDAC11 | |
| SCHEMBL15135057 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22HDAC11 | |
| SCHEMBL3905981 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22HDAC11 | |
| SCHEMBL9169888 | 0.98 | LMNA (0.52) | TSHRLMNANFKB1PMP22HDAC11 | |
| SCHEMBL1820452 | 0.91 | TSHR (0.54) | TSHRLMNANFKB1PMP22HDAC11 | |
| SCHEMBL14478080 | 0.85 | CYP2C19 (0.52) | HDAC11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6871500 | 0.85 | CYP2C19 (0.52) | HDAC11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14151935 | 0.84 | HDAC11 (0.51) | TSHRLMNANFKB1PMP22HDAC11 | |
| SCHEMBL14151934 | 0.84 | HDAC11 (0.51) | TSHRLMNANFKB1PMP22HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620494-B1 | SYNTHESIS OF POLYHYDROXYALKANOATES (PHA) WITH THIOESTER GROUPS IN THE SIDE CHAIN | CONSEJO SUPERIOR DE INVESTIG CIENTÍFICAS (CSIC) (ES) | 2017-02-22 | — | — | EP | claimed |
| US-20100256251-A1 | PROCESS FOR MODIFYING SUBSTRATES WITH GRAFTED POLYMERS | DYER DANIEL J | 2010-10-07 | — | — | US | disclosed |
| US-20060160916-A1 | Process for modifying substrates with grafted polymers | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY | 2006-07-20 | — | — | US | disclosed |
| US-5650430-A | Radicicol derivatives, their preparation and their anti-tumor activity | SANKYO COMPANY, LIMITED (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0460950-B1 | Radicicol derivatives, their preparation and their anti-tumour activity | SANKYO CO (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5597846-A | ESTERS OF RADICICOL | SANKYO COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |
| EP-0460950-A1 | Radicicol derivatives, their preparation and their anti-tumour activity | Sankyo Company Limited (JP) | 1991-12-11 | — | — | EP | disclosed |