Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 8/20 | 0.48 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608500 | 0.79 | ACHE (0.63) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL609576 | 0.77 | ACHE (0.61) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL611410 | 0.74 | ACHE (0.53) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL611971 | 0.74 | ACHE (0.53) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL608172 | 0.71 | ACHE (0.68) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL608563 | 0.70 | ACHE (0.71) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL608751 | 0.69 | ACHE (0.81) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL608520 | 0.69 | ACHE (1.00) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL608665 | 0.68 | ACHE (0.75) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL608173 | 0.68 | ACHE (0.68) | ACHEBCHEMAOAMAOBBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086860-A2 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2010-08-05 | — | — | WO | disclosed |