Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11215588 | 0.96 | MEN1 (0.46) | CA4FAHD1MEN1KMT2ABLM | |
| Bicarbonate SCHEMBL28106037 | 0.96 | MEN1 (0.46) | CA4FAHD1MEN1KMT2ABLM | |
| Oxalic Acid SCHEMBL29128883 | 0.93 | CA4 (0.44) | CA4FAHD1MEN1KMT2ABLM | |
| Bicarbonate SCHEMBL28118759 | 0.92 | MEN1 (0.43) | CA4FAHD1MEN1KMT2ABLM | |
| Bicarbonate SCHEMBL28276557 | 0.92 | MEN1 (0.43) | CA4FAHD1MEN1KMT2ABLM | |
| Acetic Acid SCHEMBL27519987 | 0.90 | CA1 (0.56) | CA4FAHD1MEN1KMT2ABLM | |
| Oxalic Acid SCHEMBL28263333 | 0.89 | CA4 (0.47) | CA4FAHD1MEN1KMT2ABLM | |
| Bicarbonate SCHEMBL5133443 | 0.88 | CA4 (0.54) | CA4FAHD1MEN1KMT2ABLM | |
| Bicarbonate SCHEMBL11732387 | 0.88 | CA4 (0.54) | CA4FAHD1MEN1KMT2ABLM | |
| Bicarbonate SCHEMBL27752585 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080056928-A1 | Functionalisation of Particles | DOW CORNING CORPORATION | 2008-03-06 | — | — | US | claimed |
| EP-1744836-A2 | PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METHOD OR APPARATUS | Dow Corning Ireland Limited (IE) | 2007-01-24 | — | — | EP | claimed |
| EP-1673163-A1 | FONCTIONALISATION OF PARTICLES | Dow Corning Ireland Limited (IE) | 2006-06-28 | — | — | EP | claimed |
| WO-2005110626-A2 | PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METOD OR APPARATUS | DOW CORNING IRELAND LIMITED (IE) | 2005-11-24 | — | — | WO | claimed |
| WO-2005039753-A1 | FONCTIONALISATION OF PARTICLES | DOW CORNING IRELAND LIMITED (IE) | 2005-05-06 | — | — | WO | claimed |
| US-12337345-B2 | Plasma coating method for coating particulate matter | PARTIX (BE) | 2025-06-24 | — | — | US | disclosed |
| EP-4237595-B1 | POWDER COATING METHOD | PARTIX (BE) | 2024-12-04 | — | — | EP | disclosed |
| US-20230398570-A1 | POWDER COATING METHOD | PARTIX (BE) | 2023-12-14 | — | — | US | disclosed |
| EP-4237595-A1 | POWDER COATING METHOD | PartiX (BE) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090518-A1 | POWDER COATING METHOD | PARTIX (BE) | 2022-05-05 | — | — | WO | disclosed |
| EP-3992330-A1 | POWDER COATING METHOD | PartiX (BE) | 2022-05-04 | — | — | EP | disclosed |
| CN-106311317-A | Catalyst and method for directly preparing light olefins from synthesis gas by one-step process | 中国科学院大连化学物理研究所 | 2017-01-11 | — | — | CN | disclosed |
| US-7758928-B2 | Organosilicone resin from liquid and gaseous organometallic precursors functionalized with common organic groups, grafted or covalently bonded amino acids proteins, enzymes and DNA; powders, gels formed in excited, unstable gas species is a non thermal equilibrium plasma system; electronics, biosensors | DOW CORNING CORPORATION (US) | 2010-07-20 | — | — | US | disclosed |
| US-20080118734-A1 | Coating Compositions | DOW CORNING IRELAND LTD. (IE) | 2008-05-22 | — | — | US | disclosed |
| US-20080056928-A1 | Functionalisation of Particles | DOW CORNING CORPORATION | 2008-03-06 | — | — | US | disclosed |
| EP-1744836-A2 | PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METHOD OR APPARATUS | Dow Corning Ireland Limited (IE) | 2007-01-24 | — | — | EP | disclosed |
| EP-1673163-A1 | FONCTIONALISATION OF PARTICLES | Dow Corning Ireland Limited (IE) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005110626-A2 | PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METOD OR APPARATUS | DOW CORNING IRELAND LIMITED (IE) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005039753-A1 | FONCTIONALISATION OF PARTICLES | DOW CORNING IRELAND LIMITED (IE) | 2005-05-06 | — | — | WO | disclosed |
| US-4001249-A | CYCLOCOUPLING N-ACYLPYRROLE AND A,A*-HALOGENOKETONE, REDUCING AGENTS | SANWA KAGAKU KENKYUSHO CO. LTD. (JA) | 1977-01-04 | — | — | US | disclosed |