SCHEMBL379950

SCHEMBL379950

O=C(O)c1cnccc1C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.54
NPC1 O15118 1/20 0.54
KDM4C Q9H3R0 6/20 0.48
MAPT P10636 3/20 0.48
ALDH1A1 P00352 3/20 0.48
KDM6B O15054 2/20 0.48
KDM4D Q6B0I6 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
KDM4A O75164 1/20 0.48
THRB P10828 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
DHODH Q02127 1/20 0.48
ASPH Q12797 1/20 0.47
RBP4 P02753 2/20 0.47
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
GAA P10253 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29369561 1.00 POLB (0.54) POLBNPC1KDM4CMAPTALDH1A1
Hydrochloric Acid SCHEMBL3827644 0.98 POLB (0.52) POLBNPC1KDM4CMAPTALDH1A1
SCHEMBL29460073 0.98 POLB (0.52) POLBNPC1KDM4CMAPTALDH1A1
SCHEMBL3934372 0.89 KDM4C (0.48) POLBNPC1KDM4CMAPTALDH1A1
SCHEMBL27743576 0.86 NPC1 (0.55) POLBNPC1KDM4CMAPTALDH1A1
SCHEMBL28242959 0.85 KDM4C (0.46) POLBNPC1KDM4CMAPTALDH1A1
SCHEMBL6220359 0.85 NPC1 (0.43) POLBNPC1KDM4CMAPTALDH1A1
SCHEMBL15514535 0.85 NPC1 (0.54) POLBNPC1KDM4CMAPTALDH1A1
SCHEMBL30017034 0.85 KDM4C (0.53) POLBNPC1KDM4CMAPTALDH1A1
SCHEMBL115907 0.85 KDM4C (0.53) POLBNPC1KDM4CMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 703 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010831-A Preparation method of 4-trifluoromethyl nicotinic acid 衢州凯沃化工有限公司 2026-05-12 CN claimed
CN-223020735-U Novel vacuum dryer for 4-trifluoromethyl nicotinic acid 成武金硕药业化工有限公司 2025-06-24 CN claimed
CN-222872188-U Energy-saving reaction kettle for preparing 4-trifluoromethyl nicotinic acid 福建盛煌生物医药科技有限公司 2025-05-16 CN claimed
CN-119983729-A Crystalline particle drying device and method for 4-trifluoromethyl nicotinic acid production 衢州凯沃化工有限公司 2025-05-13 CN claimed
CN-119954717-A Flonicamid-contained insect-killing device Process for the preparation of amides 安徽乐雍生物科技有限公司 2025-05-09 CN claimed
CN-116510672-B Acylation kettle for 4-trifluoromethyl nicotinic acid production 衢州凯沃化工有限公司 2025-04-22 CN claimed
CN-119735546-A Preparation method of 4-trifluoromethyl nicotinic acid 帕潘纳(北京)科技有限公司 2025-04-01 CN claimed
CN-222550276-U Solid-liquid separation device for 4-trifluoromethyl nicotinic acid crude product 福建盛煌生物医药科技有限公司 2025-03-04 CN claimed
CN-115928113-B Preparation method of 4-trifluoromethyl nicotinic acid 山东京博农化科技股份有限公司 2025-03-04 CN claimed
CN-119500333-A Dry grinder is used in production of 4-trifluoromethyl nicotinic acid 衢州凯沃化工有限公司 2025-02-25 CN claimed
EP-1507761-A1 PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES Bayer CropScience GmbH (DE) 2005-02-23 EP claimed
WO-2003097604-A9 PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER CROPSCIENCE GMBH (DE) 2004-05-06 WO claimed
WO-2003097604-A1 PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER CROPSCIENCE GMBH (DE) 2003-11-27 WO claimed
EP-0744400-B1 Process for producing 4-trifluoromethylnicotinic acid ISHIHARA SANGYO KAISHA (JP) 2002-09-11 EP claimed
CN-1044233-C Amide compounds and their salts, processes for their production and pesticidal compositions containing them ISHIHARA SANGYO KAISHA (JP) 1999-07-21 CN claimed
US-5708175-A Process for producing 4-trifluoromethylnicotinic acid ISHIHARA SANGYO KAISHA LTD. (JP) 1998-01-13 US claimed
EP-0744400-A2 Process for producing 4-trifluoromethylnicotinic acid ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-11-27 EP claimed
EP-0580374-B1 Pyridine amides and their salts, processes for their production and pesticidal compositions containing them ISHIHARA SANGYO KAISHA (JP) 1996-01-03 EP claimed
CN-1081670-A Amide compound and salt thereof, their manufacturing process and pesticide composition thereof ISHIHARA SANGYO KAISHA (JP) 1994-02-09 CN claimed
EP-0580374-A1 Pyridine amides and their salts, processes for their production and pesticidal compositions containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-01-26 EP claimed