Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | WDR5 | P61964 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 3/20 | 0.42 |
| ▸ | ATP4B | P51164 | 3/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.42 |
| ▸ | BRS3 | P32247 | 2/20 | 0.42 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.42 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.42 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.42 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.42 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.42 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.42 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.42 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.42 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382857 | 0.80 | AGXT (0.66) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| SCHEMBL1060082 | 0.80 | AGXT (0.66) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| Hydrochloric Acid SCHEMBL3247161 | 0.79 | AGXT (0.64) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| SCHEMBL17434548 | 0.79 | AGXT (0.64) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| SCHEMBL154027 | 0.77 | AGXT (0.66) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| SCHEMBL13011461 | 0.75 | AGXT (0.55) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| SCHEMBL1160150 | 0.75 | AGXT (0.64) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| SCHEMBL22912532 | 0.75 | AGXT (0.74) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| SCHEMBL1056427 | 0.75 | AGXT (0.69) | AGXTCYP2C9KMT2AWDR5PDE10A | |
| SCHEMBL30209599 | 0.75 | AGXT (0.64) | AGXTCYP2C9KMT2AWDR5PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378100-B2 | Phosphonate derivatives as autotaxin inhibitors | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2013-02-19 | — | — | US | disclosed |
| US-20100016258-A1 | PHOSPHONATE DERIVATIVES AS AUTOTAXIN INHIBITORS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016258-A1 | PHOSPHONATE DERIVATIVES AS AUTOTAXIN INHIBITORS | ENPP2, PHPT1, GNPAT | AGXT 77/4885CYP2C9 4835/4885KMT2A 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.