Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.75 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.69 |
| ▸ | PGR | P06401 | 7/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292490 | 0.90 | NR3C1 (0.85) | NR3C1NR3C2PGR | |
| SCHEMBL3680237 | 0.87 | NR3C1 (0.73) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292874 | 0.86 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL292809 | 0.84 | NR3C1 (0.86) | NR3C1NR3C2PGR | |
| SCHEMBL3745184 | 0.83 | NR3C1 (0.68) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL293433 | 0.82 | NR3C1 (0.83) | NR3C1NR3C2PGR | |
| SCHEMBL291671 | 0.82 | NR3C1 (0.86) | NR3C1NR3C2PGR | |
| SCHEMBL292435 | 0.82 | NR3C1 (0.91) | NR3C1NR3C2PGR | |
| SCHEMBL293132 | 0.81 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL293970 | 0.81 | NR3C1 (0.89) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203160-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | Bausch & Lomb Incorporated (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009042377-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | BAUSCH & LOMB INCORPORATED (US) | 2009-04-02 | — | — | WO | disclosed |