Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.54 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.40 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791617 | 0.93 | PIK3CA (0.56) | PIK3CACREBBPTERT | |
| SCHEMBL3789154 | 0.92 | PIK3CA (0.57) | PIK3CASCD5CREBBPHCRTR1HCRTR2 | |
| SCHEMBL2733019 | 0.91 | PIK3CA (0.57) | PIK3CASCD5CREBBPGPR142TERT | |
| SCHEMBL3798622 | 0.91 | PIK3CA (0.55) | PIK3CACREBBPGPR142TERT | |
| SCHEMBL7881809 | 0.91 | PIK3CA (0.56) | PIK3CACREBBPGPR142 | |
| SCHEMBL6126363 | 0.91 | PIK3CA (0.56) | PIK3CACREBBPGPR142 | |
| SCHEMBL2724235 | 0.91 | PIK3CA (0.56) | PIK3CACREBBPGPR142 | |
| SCHEMBL7880624 | 0.90 | PIK3CA (0.56) | PIK3CACREBBPGPR142 | |
| SCHEMBL6126319 | 0.90 | PIK3CA (0.54) | PIK3CACREBBP | |
| SCHEMBL3791762 | 0.89 | PIK3CA (0.52) | PIK3CACREBBPHCRTR1HCRTR2GPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138490-A1 | BENZOXAZEPINES AS INHIBITORS OF MTOR AND METHODS OF THEIR USE AND MANUFACTURE | EXELIXIS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |