Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.42 |
| ▸ | CDK2 | P24941 | 7/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.42 |
| ▸ | CDK1 | P06493 | 6/20 | 0.42 |
| ▸ | CDK4 | P11802 | 6/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.42 |
| ▸ | CCND1 | P24385 | 6/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37850 | 0.90 | RNASEH1 (0.47) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL38496 | 0.88 | RNASEH1 (0.46) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL3491664 | 0.81 | RNASEH1 (0.58) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL38887 | 0.80 | RNASEH1 (0.49) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL38376 | 0.80 | RNASEH1 (0.52) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL3492896 | 0.80 | RNASEH1 (0.57) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL46037 | 0.80 | MAPT (0.50) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL3492895 | 0.80 | RNASEH1 (0.51) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL16175762 | 0.80 | RNASEH1 (0.54) | RNASEH1PDE5AKDM4EMAPTALDH1A1 | |
| SCHEMBL3494840 | 0.80 | RNASEH1 (0.54) | RNASEH1PDE5AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004900-A1 | THIENOPYRIMIDINE COMPOUNDS | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | WO | disclosed |