Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400230 | 0.95 | GRIA1 (0.51) | GRIA1GPR119CKS1BSKP1SKP2 | |
| SCHEMBL2403388 | 0.81 | GPR119 (0.43) | GRIA1GPR119CKS1BSKP1SKP2 | |
| SCHEMBL23500701 | 0.79 | RET (0.39) | GRIA1 | |
| SCHEMBL30783301 | 0.78 | CCND3 (0.51) | — | |
| SCHEMBL7061217 | 0.78 | GPR119 (0.49) | GRIA1GPR119CKS1BSKP1SKP2 | |
| SCHEMBL2402317 | 0.77 | GRIA1 (0.36) | GRIA1 | |
| SCHEMBL2401761 | 0.77 | GBA1 (0.54) | GRIA1GPR119CKS1BSKP1SKP2 | |
| SCHEMBL122648 | 0.76 | PDE10A (0.53) | GRIA1GPR119CKS1BSKP1SKP2 | |
| SCHEMBL2405697 | 0.76 | NR1H2 (0.42) | GRIA1GPR119CKS1BSKP1SKP2 | |
| SCHEMBL18190024 | 0.76 | GRIA1 (0.76) | GRIA1CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088518-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010088518-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |