SCHEMBL38009

SCHEMBL38009

CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8719772 0.98
Alcohol SCHEMBL28946691 0.90
SCHEMBL5227809 0.90
Ether SCHEMBL20704371 0.88
SCHEMBL5960796 0.86
SCHEMBL20337341 0.83
SCHEMBL22463075 0.81 HSD11B1 (0.37)
SCHEMBL10346389 0.81
SCHEMBL18095036 0.80
Chlorotriphenylmethane SCHEMBL14837518 0.80 CA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8175 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117440957-B Process for the production of biotin intermediates DSM IP ASSETS B.V. (NL) 2026-05-26 CN claimed
EP-4745178-A1 ULTRA-HIGH MOLECULAR WEIGHT POLYGLUTAMIC ACID AND PREPARATION METHOD THEREFOR Imeik Technology Development Co., Ltd. (CN) 2026-05-20 EP claimed
CN-122010814-A (2S, 4R) -1-Fmoc-4- (O-allyloxycarbonyl methyl) -proline and synthesis method thereof 杭州澳赛诺医药技术有限公司 2026-05-12 CN claimed
EP-4211113-B1 HYDROXY-PYRIDINALDOXIME SCAFFOLDS CENTRE NAT RECH SCIENT (FR) 2026-02-18 EP claimed
EP-4682154-A1 PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF OLIGOSACCHARIDES REPRESENTING SEGMENTS OF O-ANTIGENS FROM DIVERSE SHIGELLA FLEXNERI SEROTYPES Institut Pasteur (FR) 2026-01-21 EP claimed
EP-4673424-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS Regeneron Pharmaceuticals, Inc. (US) 2026-01-07 EP claimed
US-12497416-B2 Acylphosphine oxide compounds and preparation methods thereof ANHUI CHICHEM CORPORATION (CN) 2025-12-16 US claimed
WO-2025245089-A1 PROCESSES FOR PREPARING TETRALIN COMPOUNDS ARCUS BIOSCIENCES, INC. (US) 2025-11-27 WO claimed
EP-4652171-A1 TOTAL SYNTHESES OF PORTIMINE A AND ANALOGUES THEREOF AS SMALL MOLECULE MODULATORS OF NMD3 The Scripps Research Institute (US) 2025-11-26 EP claimed
US-20250353838-A1 METHOD FOR PREPARING 4'-THIO-5-AZA-2'-DEOXYCYTIDINE PINOTBIO, INC. (KR) 2025-11-20 US claimed
US-5274107-A Process for synthesis of D(+) biotin COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1993-12-28 US claimed
US-5164525-A SYNTHETIC PROCESS FOR FK-506 TYPE MACROLIDE INTERMEDIATES MERCK & CO., INC. (US) 1992-11-17 US claimed
EP-0435322-A2 Benzofuran derivatives SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI &amp; CO. LTD. (JP) 1991-07-03 EP claimed
US-4837349-A Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same SUNTORY LIMITED (JP) 1989-06-06 US claimed
EP-0143323-B1 PROCESS FOR AN ANTHRACYCLINE DERIVATIVE, AND AN ANTHRACYCLINONE DERIVATIVE USEFUL FOR THE PROCESS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-10-26 EP claimed
US-4772683-A SILYLATION, AZETIDONE THIOLESTERS BRISTOL-MYERS COMPANY (US) 1988-09-20 US claimed
EP-0217243-A2 Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same SUNTORY LIMITED (JP) 1987-04-08 EP claimed
US-4639335-A ANHYDROPENICILLIN INTERMEDIATE BRISTOL-MYERS COMPANY (US) 1987-01-27 US claimed
US-4564674-A Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-01-14 US claimed
EP-0143323-A2 Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-06-05 EP claimed